LD50 and Dose Response Curve

Flashcards focused on key concepts related to toxicology, specifically LD50 and dose response curves.

LD50

The dose of a chemical that is lethal to 50% of the population of a particular species.

Dose Response Curve

A graph depicting the effect on an organism or mortality rate in a population based on the dose of a particular toxin or drug.

Threshold

The lowest dose where an effect (death, paralysis, cancer) starts to occur.

ED50

The dose concentration of a toxin or chemical that causes a non-lethal effect in 50% of the population being tested.

Acute Study

A type of dose-response study that measures effects over a short period of time.

Chronic Study

Longer-term dose-response studies that follow developmental impacts over time.

Trophic Cascades

Ecological effects resulting from organisms dying, which are not measured in acute studies.

Parts per million (ppm)

A measurement used to express the concentration of a substance in air.

Dose Concentration

The amount of a chemical present in a given volume or mass (e.g., mg/kg).