ch24 ans drugs

subdivisions of the CNS

subdivisions of this include brain and spinal cord

subdivisions of PNS

subdivisions of this include somatic and autonomic NS

basic functional unit cell of nervous system

basic functional unit of this system is the neuron

cholinergic meaning

to be liberated or activated by neurotransmitter ach

adrenergic meaning

to be liberated or activated by norepinephrine, epinephrine, or dopamine

the two main adrenergic receptors

alpha and beta receptors

alpha receptors

the adrenergic receptors which respond to adrenaline

beta receptors

the adrenergic receptors which respond to norepinephrine and epinephrine

action of adrenergic agonists

these agonists mimic sympathetic NS and produce fight or flight symptoms

actions of alpha receptor agonists

these receptor agonists influence bp and tissue perfusion

actions of beta receptor agonists

these receptor agonists mimic catecholamines ex. Epinephrine

adrenergic antagonists and how they antagonize

these antagonists block adrenergic nerve transmission usually by inhibiting neurotransmitter release or depleting stores of transmitters

the two types of cholinergic receptors

muscarinic and nicotinic receptors

action of muscarinic receptors

these innervate smooth muscle and slow heart rate

action of nicotonic receptors

these receptors affect skeletal muscle

cholinergic agonists

alternative name for parasympathomimetics, direct acting agents

selectivity of cholinergic agonists

most of these substances are nonselective but the selective ones affect only muscarinic or nicotinic receptors

where acetylcholine is located

parasympathetic neurotransmitter is found at preganglionic and postganglionic nerve endings

Name of indirect acting cholinergic agonists

anticholinesterases

Most common direct acting cholinergic agonists

examples of such are bethanechol, carbachol, cevimeline, and pilocarpine

Most common indirect acting cholinergic agonists

examples of such are ambenonium, edrophonium, neostigmine, pyridostigmine, and tacrine