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This collection of flashcards covers key vocabulary and concepts related to O2 and CO2 transport, essential for understanding the lecture on respiratory physiology.
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Gas Transport
The process of carrying gases from the alveoli to the systemic tissues and vice versa.
Oxygen transport
98.5% bound to hemoglobin in red blood cells, 1.5% dissolved in plasma.
Carbon dioxide transport
90% hydrated to form carbonic acid, 5% bound to proteins, 5% dissolved as gas in plasma.
Oxyhemoglobin
Hemoglobin bound to oxygen.
Deoxyhemoglobin
Hemoglobin without oxygen.
Carboxyhemoglobin
Hemoglobin bound to carbon monoxide.
Anemia
Condition characterized by low hemoglobin concentration.
Polycythemia
Condition characterized by high RBC count and high hemoglobin concentration.
Erythropoietin
Hormone produced by kidneys to stimulate hemoglobin and RBC production.
Hypoxia
Condition in which the body or a region of the body is deprived of adequate oxygen supply.
Percent Oxy-Hemoglobin Saturation
Percentage of oxyhemoglobin to total hemoglobin in blood.
Bohr effect
Decrease in hemoglobin's affinity for oxygen at lower pH, enhancing oxygen unloading.
2,3-BPG (2,3-bisphosphoglycerate)
A byproduct of red blood cell metabolism that increases oxygen dissociation from hemoglobin.
Sickle Cell Disease
Genetic disorder resulting from a mutation in hemoglobin, causing red blood cells to sickle.
Myoglobin
A red pigment found in striated muscle cells with a higher oxygen affinity than hemoglobin.
Dissociation Curve
Graph showing the relationship between oxygen binding and release by hemoglobin.
Chloride Shift
Process where bicarbonate ions diffuse out of red blood cells, and chloride ions diffuse in.
Carbamino-hemoglobin
Form of hemoglobin that is loosely bound with carbon dioxide.
Carbonic anhydrase
Enzyme that catalyzes the conversion of carbonic acid to carbon dioxide and water.
Reverse Chloride Shift
Process where bicarbonate enters red blood cells, and chloride ions leave.
Alveoli
Tiny air sacs in the lungs where gas exchange occurs.