Lactate/ Lactic acid
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6 Terms
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Lactate increases during
anaerobic metabolism
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Production of lactic acid
Glucose → Pyruvate → kreb’s cycle
If decreased O2 then:
Glucose → pyruvate → Lactate
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Testing for Lactate
Lactate → Lactate oxidase → pyruvate + H2O2
H2O2 + reduced dye → peroxidase → oxidized dye
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Normal Lactate value
0.5-1.5 mmol/L
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Type A Lactic Acidosis
Decreased O2
MI, heart failure, shock, pulmonary edema
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Type B Lactic Acidosis
Decreased proper metabolism → Increased lactate
Note 
Flashcards (37)