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Parts Of CNS
The central nervous system
brain and spinal cord
processes information and coordinating responses throughout the body.
PNS
is the peripheral nervous system
all nerves outside the central nervous system
connecting the brain and spinal cord to the rest of the body
Parts of PNS
Cranial Nerves
Spinal Nerves
Ganglia
Peripheral Nerves
What are the 2 cell types that produce Mylein Sheaths?
Oligodendrocytes and Schwann cells.
Oligodendrocytes
found in CNS
Insulate Axons
Increase speed of electrical signal or impulse
Random spaced Nodes Ranvier
Schwann Cells
Insulate one segment of axon
found in PNS
Increase speed of nerve impulse or electrical signal
Even spaced Nodes Ranvier
What does not have Neurilemma?
Oligodendrocytes
What does have Neurilemma?
Schwann cells
What cells are Amitotic?
Nerve cells (neuron), do not divide
Neurons are composed of
Soma, Axon, Dendrites
What is released at the axon terminal or ending?
Neurotransmitters
Bundles of Axons in CNS are called
Tracts
Bundles of Axons in PNS are called
Nerves
Dendrites produce
Graded Potential
Axons Produce
Action Potentials
Clusters in CNS are called
Nuclei
Clusters in PNS are called
Ganglia
Neuron region that receives signals
Dendrites
Neuron region that secretes neurotransmitters and send signals (transmit action potential)
Axon
Myelin Sheath
A protective covering around axons that facilitates the rapid transmission of electrical impulses along the nerve cell.
Schwann cells surround nerve fibers but coiling does not take place
Unmyelinated Axons
Myelin Sheath in CNS
Formed by Oligodendrocytes
widely spaced
no Neurilemma
Multipolar
Neuron structure- Many dendrites, One Axon together, but many
Bipolar
One Dendrite, One Axon and cell body between
Often found in Sensory Neurons
Unipolar
Found in PNS
Dendrite, axon straight together
What Neurotransmitter Stimulates Skeletal Muscle
Acetylcholine (ACh)
What are Clusters of Neuron Cell Bodies located in PNS called
Ganglia
CNS cell bodies are called
Nuclei
PNS axons are called
Nerves
CNS axons are called
Tracts
What determines Stimulus Strength?
Frequency of action potentials and Number of Neurons activated (recruitment)
What Ions are involved in setting up resting membrane potential?
Potassium (K), Sodium (Na), Chloride (Cl-)
What is much higher Intracellular?
Potassium (K) and proteins
What is much higher extracellular (outside) cell?
Sodium (Na) and Chloride (Cl-)
Ion Channels
Proteins that facilitate the movement of ions across the cell membrane
What causes Resting Membrane Potential?
More Potassium moving out cell than sodium moving in.
More leakage gates for potassium
More Positive outside and Neg charge inside cell
What Maintains Resting Membrane Potential?
Sodium Potassium Pump
Lose more positive charges than bringing in sodium, contributing to a negative charge inside the cell. Maintaining Positive on outside
Resting Membrane Potentail
-70mv
the electrical potential difference across the membrane of a resting cell, typically around -70 millivolts.
Ions can not pass through the plasma membrane without ?
Ion Channels
Leakage Channel
Always open
Leak Gate for Potassium (K)
More abundant
Potentail means
Difference between outside and inside charge of a cell's membrane, determining its electrical state.
How do Ions move through Channel Gates?
The Gate opens in response to voltage, Chemical Transmitter, or Pressure.
Ions move from High to Low concentration (Chemical Gradient)
Or toward Opposite Charge (Electrical Gradient)
Threshold Potential
-55mv
the level of depolarization needed to trigger an action potential in a neuron.
Action Potentials vary in strength
Fasle. They are always max strength
Action Potentials and Graded Potentials involve Depolarization, Repolarization, Hyperpolarization
True
Which locations are Graded Potentials found?
Dendrites and Cell Bodies
Graded Potential Characteristics
Short lived
Decrease strength with distance
Magnitude varies with strength of stimulus
Stong Graded potentials can initiate Action Potentials
Involve Chemical Gates for Depolaization
Characteristics of Action Potentials
Long Lived
Do not decrease in strength with distance
Always max strength
Involve Voltage Gates for Depolarization
Occur at Axons
Action Potentials
Occur at Dendrites and Cell Bodies
Graded Potentials
Steps for Any Kind of Membrane Potential?
Depolarization, Repolarization, Hyperpolarization
What Creates the Resting Membrane Potential?
Sodium Potassium Leak Gates
What gates are open and closed during Depolarization?
Sodium (Na) are open
Potassium (K) closed
Further away from threshold for Action Potential
Hyperpolarization
What opens Voltage Gates for Sodium?
Reaching Threshold
giving an action potential
When do sodium gates close?
Repolarization
Voltage sensitive K gates open when
Sodium channels have closed
the membrane potential starts to become less positive.
Role of Sodium Potassium Pump
Repolarization
Restores resting electrical condition of neuron
Ionic Redistribution - sodium out, potassium in
Hyperpolarization
Potassium gates remain open, causing excessive K to leave the cell, making the inside of the neuron more negative than the resting potential.
Phases of Action Potential
Resting, Depolarization, Repolarization, Hyperpolarization, Resting
Na gates open at rest
Depolarization
Na+ gates close
Action Potential
Potassium gates open
Repolarization
Hyperpolarization occurs as K+ gates remain open.
What happens if threshold isn’t met?
Will not have an Action Potential, only Graded Potential
What determines stimulus strength?
Frequency in impulse transmission or signals
When is Absolute Refractory Period?
During Depolarization and Repolarization
Characteristics of Absolute Refractory Period
Prevents neuron from generating another Action Potential
The Relative Refractory Period occurs during Hyperpolarization
True
When is Threshold Elevated?
During Relative Refractory Period - AP is harder to reach and occurs during Hyperpolarization