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_______ are substances that develop an electrical charge when dissolved in water.
Electrolytes
Nonelectrolytes are substances that do not __________ electricity.
conduct
Osmolality is the concentration of solute per __________ of water.
kilogram (kg)
The normal osmolality range is __________ mOsm/kg of water.
275-295
The _____ is the substance in which the solute is dissolved.
solvent
The ______ is the substance, or particle, that is dissolved in a solvent.
solute
______ solutions have the same osmolality as blood.
Isotonic
Hypotonic solutions have a __________ osmolality than blood and cause cells to __________.
lower; swell
Hypertonic solutions have a __________ osmolality than blood and cause cells to __________.
higher; shrink
_______ pushes fluid out of the vessel into tissue spaces.
Hydrostatic pressure
______ pulls fluid into the vessels.
Osmotic pressure
Intracellular fluid (ICF) makes up about __________% of body weight.
40
The ICF is high in __________ and low in __________.
potassium (K+); sodium (Na+)
Extracellular fluid (ECF) is high in __________ and low in __________.
sodium (Na+); potassium (K+)
The three ECF compartments are __________, __________, and __________.
Intravascular (fluid in arteries/veins), interstitial fluid, transcellular fluid
A __________ is an element or compound that separates into electrically charged ions.
electrolyte
Cations are __________ charged electrolytes, while anions are __________ charged.
positively; negatively
The main ICF cation is __________; the main ECF cation is __________.
potassium; sodium
The main ICF anion is __________; the main ECF anion is __________.
PO₄³⁻; Cl⁻
Normal blood osmolality is approximately __________ mOsm/kg.
270-300
Diffusion moves solutes from __________ to __________ concentration.
higher; lower
Osmosis moves solvent (water) from __________ to __________ solute concentration.
lower; higher
_______ occurs when water and diffusible substances move across a membrane due to hydrostatic pressure.
Filtration
Active transport moves molecules from __________ to __________ concentration and requires __________.
lower; higher; energy (ATP)
The Na⁺/K⁺ pump is an example of __________ transport.
active
The main control of fluid intake is the __________ mechanism.
thirst
The average adult daily fluid intake is ___ mL.
2200-2700
The ADH hormone is stored in the __________.
posterior pituitary gland
Natriuretic peptides come from the __________ and increase urination by blocking __________.
heart; aldosterone
The kidneys excrete about __________ mL/day or ___ mL/hour.
1500; 30-50
Sensible losses are __________ and can be __________.
measurable; measured
Insensible losses are __________ to measure and occur through the __________, __________, and __________.
hard; skin; lungs; GI tract
Insensible losses increase when a person has a __________.
fever or increased respiratory rate
Intracellular fluid (ICF) is the fluid __________ the cell.
within/inside
Most (__________) of the body’s water (H₂O) is found in the __________.
two-thirds (2/3); ICF
Extracellular fluid (ECF) is the fluid __________ the cell.
outside of
The ECF contains about __________ of the body’s total water.
one-third (1/3)
The ECF is more prone to __________ than the ICF.
loss
The three types of ECF are __________, __________, and __________ fluid.
interstitial; intravascular; transcellular
The __________ is stimulated when excess fluid is lost and __________ occurs.
thirst mechanism (hypothalamus); dehydration (hypovolemia)
Body fluid deficit is sensed by __________ in the hypothalamus.
osmoreceptors
The hypothalamus then stimulates __________ and __________ release.
thirst; antidiuretic hormone (ADH)
ADH acts in the renal __________ and __________ tubules, causing water __________.
distal; collecting; reabsorption
When there is excess water, ADH secretion is __________, leading to increased __________ excretion.
suppressed; urinary
The Renin-Angiotensin-Aldosterone System (RAAS) helps regulate __________ and __________ balance.
fluid; electrolyte
Structural changes in the __________ decrease the ability to __________ water.
kidneys; conserve
Hormonal changes lead to decreased __________ and __________ levels.
ADH; ANP
Loss of __________ tissue causes increased loss of body moisture.
subcutaneous
Older adults have a reduced __________ mechanism, leading to decreased __________ intake.
thirst; fluid
Nurses must __________ and implement treatment accordingly.
assess hydration status
Sodium (Na⁺) normal range: __________ to __________ mEq/L.
135–145
Potassium (K⁺) normal range: __________ to __________ mEq/L.
3.5–5
Calcium (Ca²⁺) normal range: __________ to __________ mg/dL.
8.5–10.5
Magnesium (Mg²⁺) normal range: __________ to __________ mEq/L.
1.6–2.6
_______ means low sodium (Na⁺).
Hyponatremia
______ means high sodium (Na⁺).
Hypernatremia
_____ means low potassium (K⁺).
Hypokalemia
______ means high potassium (K⁺).
Hyperkalemia
______ means low calcium (Ca²⁺).
Hypocalcemia
______ means high calcium (Ca²⁺).
Hypercalcemia
______ means low magnesium (Mg²⁺).
Hypomagnesemia
______ means high magnesium (Mg²⁺).
Hypermagnesemia
Sodium is the major __________ cation and the primary regulator of __________ volume.
extracellular; fluid
Sodium is important for __________ health and is reabsorbed by the __________.
brain; kidneys
Potassium is the major __________ cation and is essential for __________ contraction and __________ conduction.
intracellular; muscle; cardiac
Potassium is eliminated by the __________ and regulated by __________ and __________.
kidneys; diet; kidneys