Prions
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4 Terms
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What are prions?
Proteinaceous infectious particles. Different “infectious” agent
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What do prions not have?
Do not possess any sort of genome yet can replicate and infect host cells. No nucleic acid, no genes, just protein.
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What are prions responsible for?
Transmissible spongiform encephalopathies (TSEs), like mad cow disease (Creutzfeld-Jakob disease in humans)
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Prion replication method
Unclear. Thought to revolve around conversion of protein conformations from normal to abnormal form over time
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