BB Lec - History

Immunohematology

The branch of science that deals with the study of RBC antigens and its corresponding antibodies

Transfusion Medicine

The branch of medicine that is concerned with the process of donating, testing, processing, storing, and transfusing blood and its components.

Blood Banking

The process of donor selection and blood selection

James Blundell

He performed the first successful blood transfusion to his patient (who was obstetric)

1492

What year was the first documented human blood transfusion that took place in Ancient Rome?

Pope Innocent VII

• He was the first documented recipient of human blood

• He died from massive severe intramuscular hemolysis

1829

What year did James Blundell transfuse blood to human?

Hustin, 1914

He reported the use of sodium citrate, which was not suitable as a preservative due to toxicity

Lewisohn,1915

He discovered how to effectively utilize sodium citrate in optimal amounts as a preservative

Rous and Turner, 1916

They were able to develop citrate dextrose solution

Braxton and Hicks, 1869

They reported the use of sodium phosphate

Loutit and Mollison, 1943

They were able to introduce acid citrate dextrose

21

Both ACD and CPD can preserve blood for how many days?

Acid citrate dextrose (ACD)

• It is the first commercially used anticoagulant in BB

• It is used in apheresis procedure

Gibson, 1957

He was able to introduce Citrate phosphate dextrose (CPD)

35

Adenine is used to prolong the shelf life of blood products for up to how many days?

TRUE

TRUE OR FALSE

CPD is less acidic than ACD

CPD

It is more superior in maintaining 2,3 DPG levels

Cannula

• It has a more complex design

• It is more time consuming

• It requires the assistance of a physician

Syringe-Valve Apparatus

• It has a simpler design

• It is more time-saving

• It requires no help at all to use

Karl Landsteiner, 1901

He was able to develop the A and B antigens

He was the first to perform blood typing

Von Descatello and Sturli, 1902

They discovered the AB blood type

Landsteiner and Wiener, 1940

They developed the Rh system from Rhesus monkeys

Dr. Charles Drew, 1941

He was appointed as the director of the first ever American Red Cross Blood Bank

William HArvey

He was an English physician and scientist who described the circulation of blood

He performed the first experimental transfusion between animals

He performed the first animal-human transfusion

Audrey Smith

She contributed to RBC freezing by discovering the use of glycerol as a cryoprotective agent.

A. Solomon and J.L Fahey

They developed centrifugation technology

Weil and Ottenberg

They developed the first crossmatching procedure / compatibility testing

Ludvig Hektoen

Discovered the safety of blood transfusion through crossmatching

Dr. Yves Lapierre

Developed gel technology, which is a modernized cross matching procedure

Carlo Moreschi

Developed sensitization and lattice formation

Coombs, Mourant and Race

They developed a procedure (anti globulin test) about Moreschi's discovery

Judith Pool and Angela Shannon

They developed a blood derivative (treatment from blood product) / Cryoprecipitated AHF

Scott Murphy and Frank Gradner

They developed feasibility of storing platelets @ RT