BB Lec - History

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Immunohematology

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Description and Tags

36 Terms

1

Immunohematology

The branch of science that deals with the study of RBC antigens and its corresponding antibodies

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2

Transfusion Medicine

The branch of medicine that is concerned with the process of donating, testing, processing, storing, and transfusing blood and its components.

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3

Blood Banking

The process of donor selection and blood selection

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4

James Blundell

He performed the first successful blood transfusion to his patient (who was obstetric)

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5

1492

What year was the first documented human blood transfusion that took place in Ancient Rome?

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6

Pope Innocent VII

  • He was the first documented recipient of human blood

  • He died from massive severe intramuscular hemolysis

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7

1829

What year did James Blundell transfuse blood to human?

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8

Hustin, 1914

He reported the use of sodium citrate, which was not suitable as a preservative due to toxicity

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9

Lewisohn,1915

He discovered how to effectively utilize sodium citrate in optimal amounts as a preservative

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10

Rous and Turner, 1916

They were able to develop citrate dextrose solution

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11

Braxton and Hicks, 1869

They reported the use of sodium phosphate

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12

Loutit and Mollison, 1943

They were able to introduce acid citrate dextrose

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13

21

Both ACD and CPD can preserve blood for how many days?

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14

Acid citrate dextrose (ACD)

  • It is the first commercially used anticoagulant in BB

  • It is used in apheresis procedure

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15

Gibson, 1957

He was able to introduce Citrate phosphate dextrose (CPD)

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16

35

Adenine is used to prolong the shelf life of blood products for up to how many days?

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17

TRUE

TRUE OR FALSE

CPD is less acidic than ACD

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18

CPD

It is more superior in maintaining 2,3 DPG levels

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19

Cannula

  • It has a more complex design

  • It is more time consuming

  • It requires the assistance of a physician

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20

Syringe-Valve Apparatus

  • It has a simpler design

  • It is more time-saving

  • It requires no help at all to use

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21

Karl Landsteiner, 1901

He was able to develop the A and B antigens

He was the first to perform blood typing

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22

Von Descatello and Sturli, 1902

They discovered the AB blood type

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23

Landsteiner and Wiener, 1940

They developed the Rh system from Rhesus monkeys

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24

Dr. Charles Drew, 1941

He was appointed as the director of the first ever American Red Cross Blood Bank

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25

William HArvey

He was an English physician and scientist who described the circulation of blood

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26

He performed the first experimental transfusion between animals

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27

He performed the first animal-human transfusion

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28

Audrey Smith

She contributed to RBC freezing by discovering the use of glycerol as a cryoprotective agent.

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29

A. Solomon and J.L Fahey

They developed centrifugation technology

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30

Weil and Ottenberg

They developed the first crossmatching procedure / compatibility testing

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31

Ludvig Hektoen

Discovered the safety of blood transfusion through crossmatching

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32

Dr. Yves Lapierre

Developed gel technology, which is a modernized cross matching procedure

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33

Carlo Moreschi

Developed sensitization and lattice formation

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34

Coombs, Mourant and Race

They developed a procedure (anti globulin test) about Moreschi's discovery

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35

Judith Pool and Angela Shannon

They developed a blood derivative (treatment from blood product) / Cryoprecipitated AHF

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36

Scott Murphy and Frank Gradner

They developed feasibility of storing platelets @ RT

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