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Lymphatic system
consists of lymphatics, organs, tissues, and lymph
What are the main functions of the lymphatic system?
collect and return excess interstitial fluid to the blood stream
transports dietary lipids and lipid soluble vitamins
serves as a site of immune function
houses phagocytic cells and lymphocytes
What is the flow of lymph?
lymphatic capillaries → lymphatic vessels (passing through nodes) → lymphatic trunks → lymphatic ducts
the lymphatic system is highly ______.
permeable
What does it mean for the lymphatic system to be highly permeable?
endothelial cells are not tightly bound allowing fluid to leak in
collagen anchors the lymphatic capillaries to the surrounding tissue allowing any increase in interstitial fluid to open these valves
Lacteals
brings fat and soluble vitamins from intestines into vasculature.
What is the flow of fat/fat soluble vitamins in lacteals?
intestines (chylomicrons) → lymphatic vessels (chyle) → heart → blood → liver (chylomicron remnant) → blood (cholipoprotein) → tissues, particularly adipose (triglycerides)
Why can substances like pathogens, protein, and cancer cells enter the lymphatic capillaries?
high permeability
lymph nodes
encapsulated bean shaped organs containing lymphocyte
what is the function of lymph nodes?
filter the lymph
immune system activation
lymph trunks merge to form two main ducts:
left (thoracic) lymphatic duct
Right lymphatic duct
left (thoracic) lymphatic duct
drains lymph from the legs, abdomen, left arm, left thorax, neck and head
drains into the left jugular/subclavian vein
right lymphatic duct
drains lymph from the right arm, right thorax, neck, and head
drains into the right jugular/subclavian vein