Genetics - Lecture 4: Genes on the same chromosome: when Mendel goes wrong

When does confidence in inferred genotype increase?

Increases as the number of offspring counted increases.

Bateson and Punnett experiment

had results that challenged the 9:3:3:1 Mendelian ratio when doing their dihybrid cross

p-value <= 0.05

significant difference between expected and observed results

p-value = 0.05

difference occurred by chance

Recombination frequencies:

a measure of the physical distance between genes on a chromosome

Hemizygous

the presence of only one allele for a characteristic, as in X-linkage; hemizygosity makes descriptions of dominance and recessiveness irrelevant

Synapsis

Pairing of homologous chromosomes gene by gene