C1.2 Cell respiration

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115 Terms

1
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What are nucleotides?

Nucleotides are the subunits of RNA and DNA, consisting of a nitrogen-containing base, a five-carbon sugar, and one or more phosphate groups.

2
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Why is ATP considered a nucleotide?

ATP is a nucleotide because it consists of the base adenine, the five-carbon sugar ribose, and three phosphate groups.

3
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Why is ATP described as the energy currency of the cell?

ATP is used for temporary energy storage and energy transfer within cells.

4
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What makes ATP suitable for its role in energy transfer?

ATP is water-soluble, stable at neutral pH, and cannot pass freely through membranes.

5
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What happens during ATP hydrolysis?

The third phosphate group of ATP is removed, forming ADP, phosphate, and releasing energy.

6
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How much energy is released by ATP hydrolysis?

A relatively small amount of energy is released, sufficient for many cellular processes.

7
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What are the three main types of cellular activities requiring ATP?

Synthesizing macromolecules, active transport, and movement.

8
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Why is ATP needed for synthesizing macromolecules?

ATP provides the energy needed to link monomers into polymers during anabolic reactions.

9
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How does ATP contribute to active transport?

ATP causes reversible changes in the conformation of pump proteins to move ions or particles against concentration gradients.

10
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Why is ATP required for cellular movements?

ATP provides energy for moving components like chromosomes and vesicles and for changing cell shapes during processes like cytokinesis.

11
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Why does ATP release energy when converted to ADP?

ATP contains more chemical potential energy than ADP, so energy is released during the conversion.

12
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What is the role of phosphorylation in cellular processes?

Phosphate groups from ATP can attach to molecules, releasing energy for conformational or chemical changes.

13
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What processes regenerate ATP from ADP and phosphate?

Cell respiration, photosynthesis, and chemosynthesis regenerate ATP.

14
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Why is ATP continually regenerated in cells?

The quantity of ATP in a cell is small, and processes requiring energy stop without constant regeneration.

15
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What happens to cells without ATP?

Cells degrade within minutes, leading to irreparable damage and cell death.

16
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What happens to excess energy during ATP-ADP interconversion?

Some energy is transformed into heat.

17
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What is cell respiration?

A process where carbon compounds are oxidized to release energy for producing ATP.

18
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What are common respiratory substrates?

Glucose and fatty acids are the main substrates.

19
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How do oxygen and carbon dioxide move during respiration?

They move independently across the plasma membrane by simple diffusion.

20
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Why are gas exchange and cell respiration interdependent?

Gas exchange supplies oxygen and removes CO2, while respiration creates concentration gradients for diffusion.

21
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What are the two types of cell respiration?

Aerobic (using oxygen) and anaerobic (not using oxygen).

22
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Why is anaerobic respiration used in muscles?

It supplies ATP rapidly during high-power muscle contractions.

23
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What is a waste product of anaerobic respiration in muscles?

Lactate (lactic acid).

24
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What limits anaerobic respiration in humans?

The body's tolerance to lactate concentration limits anaerobic respiration.

25
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What is oxygen debt?

The oxygen needed to break down lactate after anaerobic respiration.

26
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What happens during oxidation and reduction?

Oxidation is the loss of electrons, and reduction is the gain of electrons.

27
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What is NAD and its role in respiration?

NAD is an electron carrier that accepts and loses electrons reversibly during respiration.

28
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What happens when NAD+ is reduced?

NAD+ accepts two electrons and one proton, becoming NADH.

29
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What is glycolysis?

A metabolic pathway that converts glucose into two molecules of pyruvate.

30
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What is the net yield of ATP in glycolysis?

Two ATP molecules per glucose.

31
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What is the role of NAD in glycolysis?

NAD is reduced to NADH, carrying electrons for further reactions.

32
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How is NAD regenerated in anaerobic respiration?

Hydrogen from NADH is transferred to pyruvate, forming lactate or ethanol.

33
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What is lactic fermentation?

A process where pyruvate is converted to lactate to regenerate NAD for glycolysis.

34
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How does lactic fermentation preserve food?

Lactic acid lowers pH, preventing bacterial or fungal decomposition.

35
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What is ethanol fermentation?

A process where pyruvate is converted to ethanol and carbon dioxide to regenerate NAD.

36
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Which organism performs ethanol fermentation?

Yeast, a facultative anaerobe.

37
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What are the uses of ethanol fermentation?

Baking (creating bubbles in dough) and brewing.

38
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What is yeast?

A unicellular fungus that respires aerobically or anaerobically.

39
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What are the stages of glycolysis?

Phosphorylation, lysis, oxidation, and ATP formation.

40
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What happens in the phosphorylation stage of glycolysis?

ATP adds phosphate groups to glucose, forming fructose-1,6-bisphosphate.

41
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What is the lysis stage of glycolysis?

Fructose-1,6-bisphosphate splits into two triose phosphate molecules.

42
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What happens during oxidation in glycolysis?

Triose phosphate is oxidized, forming bisphosphoglycerate and reduced NAD.

43
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What is the final stage of glycolysis?

ATP is formed by transferring phosphate groups from bisphosphoglycerate to ADP.

44
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What is the overall outcome of glycolysis per glucose molecule?

Two pyruvates, two NADH, and a net gain of two ATPs are produced.

45
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Why is glycolysis useful in anaerobic conditions?

It produces ATP without requiring oxygen.

46
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What is required for glycolysis to continue?

Replenishment of glucose, ADP, and NAD.

47
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What happens if glucose runs out in glycolysis?

Glycolysis stops unless glucose is transported or stored.

48
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How does NAD regeneration allow glycolysis to continue?

Regeneration ensures NAD is available for the next round of glycolysis.

49
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What is the role of decarboxylation in ethanol fermentation?

Pyruvate is converted to ethanal by removing carbon dioxide.

50
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What happens to ethanal during ethanol fermentation?

It is reduced to ethanol by NADH.

51
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What are examples of foods made by lactic fermentation?

Yogurt, kimchi, sauerkraut, and silage.

52
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What is a facultative anaerobe?

An organism that can respire aerobically or anaerobically.

53
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How does anaerobic respiration maximize muscle power?

It provides rapid ATP production for short bursts of activity.

54
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What limits the duration of anaerobic respiration?

Accumulation of lactate restricts prolonged use.

55
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What is the Benedict’s test?

A test for certain sugars that involves a reduction reaction with copper ions.

56
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What happens to copper ions in the Benedict’s test?

Copper ions are reduced to copper atoms, forming a red or orange precipitate.

57
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What does yeast produce during anaerobic respiration in dough?

Carbon dioxide and ethanol

58
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Why does dough swell or "rise"?

Carbon dioxide forms bubbles within the dough.

59
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What happens to ethanol in dough during baking?

It evaporates.

60
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What is the aim of fermentation when brewing wine or beer?

To produce ethanol rather than carbon dioxide.

61
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What type of sugar source is used to make wine?

Grape juice with a naturally high sugar concentration.

62
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What is the primary ingredient in beer production?

Barley grains mixed with water.

63
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What enzyme is needed to convert starch into sugar during beer production?

Amylase.

64
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Why does anaerobic respiration occur during brewing?

Diffusion of oxygen into the liquid in the tank is limited.

65
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What happens when the ethanol concentration reaches about 15% during brewing?

Ethanol fermentation stops because it becomes toxic to the yeast.

66
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What is bioethanol used for?

As a renewable energy source and fuel for vehicles.

67
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What are common feedstocks for bioethanol production?

Sugarcane and corn (maize).

68
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How is ethanol purified in bioethanol production?

By distillation.

69
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What molecule is oxidized in aerobic respiration for higher ATP yield?

Pyruvate.

70
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What process links glycolysis to the Krebs cycle?

The link reaction.

71
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What does decarboxylation in the link reaction do?

Removes carbon dioxide from pyruvate to form a two-carbon molecule.

72
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What molecule accepts electrons during the link reaction?

NAD, converting it to reduced NAD.

73
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What molecule is formed when the acetyl group binds to coenzyme A?

Acetyl coenzyme A.

74
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Where does the link reaction occur?

In the matrix of the mitochondrion.

75
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What molecule combines with acetyl groups in the Krebs cycle?

Oxaloacetate.

76
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What is the six-carbon molecule produced in the Krebs cycle?

Citrate.

77
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How many decarboxylation reactions occur per turn of the Krebs cycle?

Two.

78
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What are the byproducts of decarboxylation in the Krebs cycle?

Carbon dioxide.

79
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What are the carriers of electrons in the Krebs cycle?

NAD and FAD.

80
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How many ATP molecules are produced directly per turn of the Krebs cycle?

One.

81
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What is the purpose of the electron transport chain (ETC)?

To generate and maintain a proton gradient across the inner mitochondrial membrane.

82
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Where does the ETC occur?

In the inner mitochondrial membrane.

83
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What molecule donates electrons to the first carrier in the ETC?

Reduced NAD.

84
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What is the energy released by electron transfer in the ETC used for?

Pumping protons across the inner mitochondrial membrane.

85
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How many protons are pumped per pair of electrons from reduced NAD in the ETC?

Ten.

86
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How many protons are pumped per pair of electrons from reduced FAD in the ETC?

Six.

87
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What gradient is created by the ETC?

A proton gradient.

88
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What is the enzyme that synthesizes ATP using the proton gradient?

ATP synthase.

89
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What is the process of coupling the proton gradient to ATP synthesis called?

Chemiosmosis.

90
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Where are the active sites for ATP production located on ATP synthase?

In the globular part projecting into the matrix.

91
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What is the role of the rotor in ATP synthase?

It rotates, transferring energy to synthesize ATP.

92
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How many β subunits does ATP synthase have?

Three.

93
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How many ATP molecules are produced per full rotation of ATP synthase?

Three.

94
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How many protons are needed to cause one full rotation of ATP synthase?

Ten.

95
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What is the ATP yield per reduced NAD?

2.5 ATP.

96
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What is the ATP yield per reduced FAD?

1.5 ATP.

97
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What is the terminal electron acceptor in the ETC?

Molecular oxygen.

98
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What happens to oxygen after accepting electrons in the ETC?

It combines with hydrogen ions to form water.

99
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What happens if oxygen is unavailable for aerobic respiration?

The ETC stops functioning, and reduced NAD accumulates.

100
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How many ATP molecules are produced per glucose molecule in anaerobic respiration?

Two.