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the endocrine system includes glands that secrete substances called ___
the ____ system includes cells, tissues and organs that are collectively called ___
endocrine system, endocrine glands
the glands secrete chemical substances called which travel in ___
hormones, the bloodstream
when these substances reach the, theyir . They bind to ___, resulting in a change in the functioning of the cells.
target cells and receptors
__ glands secrete __ into the bloodstream to change functioning of target cells a distance away.
Endocrine glands; hormones
glands secrete substances (like _) into ducts which open onto free surfaces
Exocrine glands; sweat
_ secretions are released from one cell and alter the functioning of neighboring cells
paracrine
_ secretions have their effect on the same cell that released them
autocrine
which of following are functions of the endocrine system?
regulates water and electrolyte balance
regulates metabolism
controls reproduction and development
regulates growth
The hypothalamus uses nervous stimulation to control the secretion of hormones from which gland
posterior pituitary
which of the following glands is found in the brain?
pituitary gland
GH - Growth hormone
increases size and division rate of body cells
PRL - Prolactin
sustains milk production after birth
TSH - Thyroid stimulating hormone
controls thyroid gland secretions
ACTH - Adrenocorticotropic hormone
controls adrenal cortex secretions
FSH - Follicle-stimulating hormone
stimulates development of eggs and sperm
LH - Luteinizing hormone
causes secretion from ovaries and testes
ADH - antidiuretic hormone
causes kidneys to conserve water
OT - oxytocin
affects muscle contraction of uterus and mammary glands
Specific cells in the kidney can respond to changes in blood pressure. If the blood pressure drops, these cells release the enzyme _
renin
the enzyme converts a blood protein called to the peptide _
angiotensinogen; angiotensin I
an enzyme in the lungs then converts the peptide to whose function is to stimulate the _ to release the hormone _
angiotensin II; adrenal cortex: aldosterone
the hormone acts to _ sodium ions and, indirectly, water. This process will increase blood volume and blood pressure
conserve
Which of the following hormones is released when blood glucose levels are elevated?
Insulin
what is the correct order of hormones released during a stress response( general adaption syndrome)?
CRH → ACTH → cortisol
which of the following is a physiological stressor?
extreme heat
Decreasing levels of which hormone are associated with the declining strength that occurs with aging in the skeletal and muscular systems?
GH - growth hormone
Epinephrine is a hormone that cannot cross the plasma membrane. what classification hormone is it?
protein or amine
since the hormone epinephrine cannot enter the cell, what chemical serves as the 2nd messenger for the hormone?
cAMP
a peptide hormone can enter the cell directly (TRUE OR FALSE)
false
Once in the interstitial fluid, the only thing a hormone can affect is a target cell (TRUE OR FALSE)
true
aldosterone, a hormone made from cholesterol, has its receptors on the cell membrane. (TRUE OR FALSE)
False
The activation of intracellular proteins in the cell is the action of a peptide hormone. ( TRUE OR FALSE)
true
what gland release ACTH?
Pituitary gland
what is the action of ACTH?
stimulate the release of hormones from the adrenal cortex
if the ACTH stimulation test is positive for addison disease, what is expected to happen to blood levels of cortisol one hr after the ACTH injection?
Cortisol levels will be unchanged
Excess or insufficient secretion of a hormone can result in the inability to maintain homeostasis TRUE OR FALSE
true
Endocrine disorders can be due to an inability of a gland to make hormones
true
The pancreatic hormones function together to stabilize blood glucose concentration through a negative feedback mechanism. The pancreatic hormone lowers blood glucose levels, while raises blood glucose levels
insulin; glucagon
Which of the following hormones are produced by the anterior pituitary?
GH - growth hormone
PRL - prolactin
TSH - thyroid-stimulating hormone
ACTH - adrenocorticotropic hormone
a steroid hormone enters a cell directly TRUE OR FALSE
true
what is the purpose of the hormone receptor complex moving into the nucleus?
it will cause a transcription of DNA
what is the final effect of the steroid hormone activation of the cell?
production of proteins
hormone enters the cell directly
steroid hormone
receptor is inside the cell
steroid hormone
stimulates transcription of DNA
steroid hormone
receptor is on the cell membrane
nonsteroid hormone
results in metabolic changes in the cell
steroid hormone and nonsteroid hormone
a female with a recent history of broken bones, ulcers, and kidney stones. The physician finds that they have unusually high blood levels and immediately suspects that they are suffering from an excess of _
parathyroid hormone
where is the thymus gland located?
in the mediastinum
Which organs are also components of the endocrine system because, in addition to other functions, they produce hormones?
thymus gland
reproductive organs
digestive tract
heart and kidneys
Why is there a higher level of thyroid hormone secreted in cases of pituitary tumors?
The thyroid hormone is secreted in response to hormonal stimulus from the anterior pituitary
Would insulin, a hormone that is secreted in response to humoral stimulus, be affected by the pituitary gland?
No, hormones controlled by humoral stimuli would not be affected directly by the pituitary tumor
Prolactin has a permissive effect on oxytocin in breast tissue. If prolactin levels were high, but a drug had blocked oxytocin receptors, what would be the result?
oxytocin would have LESS of an effect on the target cells
Glucagon and insulin have antagonistic effects; glucagon signaling results in an increase in blood glucose concentration. What do you expect is the result of insulin signaling?
a decrease in blood glucose concentration
When is hormone receptor downregulation likely to occur?
if a hormone is a secreted at higher than usual levels
in cases of higher-than-average insulin signaling, which of the following is likely to happen in target cells over time?
insulin receptor downregulation
Exercising muscles upregulates transporters independently of insulin signaling. Therefore, why is exercise a useful therapy for an individual with type II diabetes?
Exercise lowers blood glucose levels and therefore lowers insulin levels
Why might the oversecretion of insulin reduce glucose uptake by nerve cells?
Too much insulin pulls a lot of glucose out of the blood at a fast rate, which can cause low blood sugar, and since nerve cells do not rely on insulin and take glucose straight from the blood, if there isn't enough glucose left, they end up not getting what they need
what hormone is released in response to low oxygen levels in the blood due to low red blood cells?
erythropoietin
What gland produces melatonin?
pineal gland
what hormone is involved with the development of immunity?
thymosin