Fluoroquinolones and other antibiotics

Ciprofloxacin

Cipro

Fluoroquinolone antibiotic

Levofloxacin

Levaquin

Fluoroquinolone antibiotic

Azithromycin

Zithromax

Macrolide antibiotic

Erythromycin

EES

Macrolide antibiotic

Clarithromycin

Biaxin

Macrolide antibiotic

Gentamicin

Garamycin

Level-monitored antibiotic

Tobramycin

N/A

Level-monitored antibiotic

Vancomycin

Vancocin

Level-monitored antibiotic

‘Red man syndrome’ risk

Metronidazole

Flagyl

Antibiotic

Inhibits alcohol metabolism

Clindamycin

Cleocin

Antibiotic

Linezolid

Zyvox

Antibiotic

Risk of serotonin syndrome

Doxycycline

Vibramycin

Antibiotic

Nitrofurantoin

Macrobid

Antibiotic

Trimethoprim/Sulfamethoxazole

Bactrim

Antibiotic

Side effects of fluoroquinolones?

-Tendon rupture

-QT prolongation

-GI upset

-C Diff infection

Interactions with fluoroquinolones?

-Bonds to cations (antacids, iron, calcium) and can’t be absorbed

-QT prolongation risk with other QT prolongators

Side effects of macrolide antibiotics?

-QT prolongation

-C Diff infection

Side effects of level-monitored antibiotics?

-Ototoxicity

-Nephrotoxicity

-Red man syndrome (vancomycin)

Which antibiotic treats C. Difficile infection?

Vancomycin