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Step 1
A wave of action potentials spreads out from the neuromuscular junction and enters the T-tubules.
Step 2
Action potentials in the T tubules lead to diffusion of calcium from the sarcoplasmic reticulum into the cytosol, where the thick and thin filaments are found.
Step 3
Calcium binds to troponin of the thin filaments
Step 4
The troponin-tropomyosin complex changes shape and exposes the active sites on the actin filaments.