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introduction
main system of measurement used in pharmacy calculations
international system of units (SI)
AKA metric system
also avoirdupois system and apothecaries system
SI unit for length
meter (m)
SI unit for volume
liter (L)
SI unit for weight
kilograms (kg)
avoirdupois unit for weight
ounce or pound
avoirdupois unit for volume
quart or gallon
apothecaries unit for weight
grain or scruple or dram
drug doses usually administered in...
milligrams (mg) or milliliters (mL)
stock volumes of liquid drug products often expressed as...
concentrations
ex: 400mg/5mL
many medications require dosing to be based on...
patient's weight (usually in kg)
ex: 50mg/kg
lab values typically expressed as...
number of milligrams (mg) of detected value per deciliter (dL) of blood
ex: 200mg/dL
measurements of length & its conversion factors
1m = 100cm = 1000mm = .1km
inch to cm
1in = 2.54cm
measurements of volume & its conversion factors
1L = 1000mL
1mL = 1cm^3
1floz = 29.57mL (or 30mL)
1pt = 473mL (or 480mL)
1tsp = 5mL
1tbs = 15mL
1qt = 946mL
measurements of weight & its conversion factors
1g = 1000mg = .1kg
1mL H2O = 1g
2.2lbs = 1kg
1oz = 28.35g
dose
quantity of medication taken by a patient for an intended therapeutic effect
single dose
quantity of medication taken at one time
daily dose
quantity of medication taken in one 24hr period
total dose
quantity of medication taken during the entire course of therapy
loading dose
a larger than usual initial amount of medication intended to rapidly raise the blood drug level to a therapeutic level
dosage regimen
schedule on which the patient is intended to take prescribed medications
usual dosage range
quantity of medication that may be prescribed within the guidelines of usual medical practice
(usually broken down into specific patient populations like adults, pediatrics, patients w/ renal disease, etc.)
Pharmacists must verify that ordered medications...
fall into the usual dosage range w/ a typical dosage regimen
(if it doesn't, call the prescriber to clarify the dose)
routes of administration
oral (by mouth)
sublingual (under the tongue)
parenteral (injection)
topical (on skin)
conjunctival (in eye)
inhaled (into lung)
intranasal (into nose)
rectal (rectum)
depending on route of administration...
alteration in calculation of a drug dose may be necessary
to measure and administer oral liquids (use what?)
oral syringes or medication cups (AKA pharmaceutical grade medication administration tools)
^ b/c household spoons and utensils aren't standardized
unit: drop (gtt)
(what's it used for & one drop equals what?)
used for liquid medications intended for conjunctival use or oral liquids for pediatric patients
standard volume in one drop = 15 to 20mL
medications can also be dosed based on...
patient's body surface area (BSA)
- used in pediatric patients and in patients taking chemotherapy
- BSA unit = m^2
- calculated using a nonogram or mosteller formula --> the square root of (height x weight)/3600 (where height is in cm and weight is in kg)
prescription
an order for a medication issued by a medical provider w/ appropriate licensure + authority in state which they practice
medication order
(similar concept to prescription that's used in hospitals and institutional settings)
- timing of doses to be administered expressed in military time
prescriptions & medication orders
- can be written, transmitted electronically, sent by telephone, or faxed
- various legal + regulatory requirements for prescriptions and medication orders to be considered valid & complete
- pharmacists must verify each prescription/medication order is correct in format & content
pharmacists and health care providers should follow the (1) ______________ when (2) ________________
(1) "5 rights"
(2) ordering, verifying, or administering medications to patients
"5 rights"
verify the order is the right drug and right dose
for the right patient
and is given at the right time
via the right route of administration
pharmacists need to verify... if being dispensed to a patient to use at home
...the labeling of medication with directions for use is correct...
used to signify quantities on a prescription or medication order
roman numerals
(when a larger numeral precedes smaller numerals, the sums of all numerals are added together)
(when a smaller numeral precedes a larger numeral, the difference b/w the two numerals demonstrates the intended value)
roman numeral for 1/2
ss
roman numeral for 1
I
roman numeral for 5
V
roman numeral for 10
X
roman numeral for 50
L
roman numeral for 100
C
roman numeral for 500
D
roman numeral for 1000
M
roman numeral for 12
XII
roman numeral for 90
XC
roman numeral for 44
XLIV
aa
of each
disp
dispense
ft
make
qs
a sufficient quantity
qs.ad
a sufficient quantity to make
sig. (sigma)
write (directions for label)
ac
before meals
am
morning
ATC
around the clock
BID
twice daily
c
with
d
day
h
hour
HS
at bedtime
NPO
nothing by mouth
Q
every
QAM
every morning
Q8H
every 8 hours
QID
4 times daily
STAT
immediately
TID
3 times daily
ut dict
as directed
wk
week
ad
right ear
as
left ear
au
both ears
ID
intradermal
inj
injection
IM
intramuscular
IT
intrathecal
IV
intravenous
IVP
intravenous push
IVPB
intravenous piggyback
NGT
nasogastric tube
od
right eye
os
left eye
ou
both eyes
PO
by mouth
rect
rectally
SL
sublingually
Sub-Q/SC
subcutaneously
Top
topically
PV
vaginally
BSA
body surface area
cm3
cubic centimeters or milliliters
g
gram
gtt
drop
IU
international unit
DO NOT USE b/c mistaken for IV (intravenous) or the number 10 SO write international unit
lb
pound
kg
kilogram
L
liter
m2
square meter
mcg
microgram