TSGs and treatments

how is cancer treatment decided

Decided from the Stage and grade of cancer, biomarker testing, patient overal health (overall or liver disease ) kidney and patient preference.

Local treatment

Surgery and radiation therapy are the main cancer treatments, as well as combining it with medication, it's the best way to remove the cancer.

local treatment (radiation)

high-energy X-ray beam aimed for tissue penetration,

aims for radiation

Aim: 1) eradicate the residual microscopic disease (cancer)  and 2) shrink tumour masses to relieve

Targeted therapy

Targeted therapy is a cancer therapy that affects the cancer cells more than the normal cells

example of target therapy

Monoclonal antibody reacts with the antibodys, triggering immunological reactions.

examplle of Monoclonal antibody

Trastuzumab blocks the Her2 receptors in breast cancer

what is TCG (tumer suppresser genes )

Tumor Suppressor Genes (TSGs) are genes that normally inhibit cell growth, repair DNA, or trigger apoptosis to prevent uncontrolled cell division.

how does TCG work

acts as a brake of the cell cycle prevents tumour formation and deletion

When TSGs Mutate:

Uncontrolled Cell growth leads to tumour formation and loss of function example TP53 and BRCA1

what hall marker does it effect when mutated

Evading Growth Suppressors