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293 Terms
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Draganski
They used MRIs of medical students before and after their final exams and saw that there was a change in volume of the hippocampus - evidence of plasticity in humans. This cannot be used to provide causal inferences, however the degree of similarity between the findings of this research and Kemperman’s are significant. They both have high reliability and when you combine the research it suggests that cognitive challenge can alter the hippocampus, which demonstrates the nature of plasticity.
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Kemperman
They put rats into an enriched environment with notable cognitive challenge (difficult maze etc) and saw that there were new neurons in the rats hippocampi.
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Mass action (Lashley)
This suggests that the degree of impairment after damage is directly proportional to the amount of brain damaged, not the location.
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Nikbakhitian et al (2021)
They used an accelerometer (objective measure) derived sleep onset time (SOT) for over 100, 000 participants.
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Nerves
These are cylindrical bundles of several thousand neuron axons (fibres)
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Echolocation
This is something that blind people can learn to do to "see "the surroundings. Auditory information is processed by the visual cortex which demonstrates adaptation to maximise functioning.
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McGuire et al
Found that London taxi drivers had more grey matter in their brain, and a bigger posterior hippocampus than the control group when tested using MRI machines.
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Chronotypes
Peoples natural inclinations for wake and sleep patterns, so the technicalities about the precise time of the circadian rhythm can be partly influenced by genes. Approx 1/3 are larks, 1/3 are night owls and 1/3 have a mixed pattern. Many night owls to becoming chronically socially jet lagged, this can result in diminished integrity of white matter in the brain and increased risks for things like depression and alcohol use.
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Functional recovery
When the brain can restore skills or behaviours after damage has occurred.
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Szaflarski et al (2006)
Found that language became more lateralised to the left hemisphere as age increased, but after 25 it became increasingly less lateralised.
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Freeze response
A momentary parasympathetic brake on the motor system as a form of behavioural inhibition, controlled by the periaqueductal grey. (Gray et al)
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Biological rhythms
Patterns of physiological processes that occur and recur with a predictable regularity.
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Post-mortem examinations
Involve studying the actual, physical brain of a deceased individual to look for lesions or causes for any phenomenological afflictions or mental health disorders an individual may have struggled with. They are used to find the underlying neurobiology of a particular behaviour and a brain may be compared to a neurotypical control.
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Human NS
A complex network of nerve cells and fibres that enables the brain to receive information about the environment and to command responses.
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Luckow et al (1998)
Found that "seeking and using social support "was massively significant in females (but not at all in males), (p
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Functional magnetic resonance imaging
Measures changes in brain activity by looking for changes of blood flow to certain areas. This allows researchers to create a visual map of activity in the brain, rather than just anatomy, to deduce that certain regions are involved in task performance.
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PNS
This includes all the nerves external to the CNS.
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Split brain research
Refers to the studying of individuals who have had split- brain surgery, in order to understand more about the individual specialisms of each hemisphere.
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CNS
This is the major division of the NS that includes all nerves in the central system. Its 2 main processes are controlling behaviour and regulating the body’s physiological processes.
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Tend and befriend
This response is controlled by oxytocin release and is known for its affiliative behaviours. Oxytocin could also inhibit glucocorticoids (stress hormones) and have a protective role.
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Wernicke’s area
Responsible for the understanding and comprehension of language and is found in the posterior portion of the left temporal lobe. (fluency aphasia)
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Autonomic NS
Works with smooth (organ) muscle to affect action and control involuntary bodily processes.
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Endocrine system
This uses a negative feedback loop (this means the system responds when the conditions are no longer ideal) to maintain homeostasis (the regulation of internal bodily functions in an optimal state)
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FM (radio)
The motor cortex is in the frontal lobe
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PS (play station)
The somatosensory cortex is in the parietal lobe.
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wTAf (teaching assistant/ wtf)
Wernicke’s area in the auditory cortex in the temporal lobe can cause fluency aphasia
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OV (ovulation)
The visual cortex is in the occipital lobe
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Two main language centres in the brain
Broca’s area and Wernicke’s area
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Two regions of Broca’s area
For language and demanding cognitive tasks (Fedorenko et al, 2012)
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The Principle of Equipotentiality
This suggests that every aspect of the cortex has equal potential to perform a function (this is how there can be a recovery of function without neural/ cortex recovery)
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Re-routing
A neuron that has lost its target seeks a new connection to enable communication around the damaged area
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Sprouting
Nerve fibres grow and become bushier to make new connections and enable connection
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Recruitment
The homologous area on the opposite hemisphere begins to perform specific tasks previously undertaken by the damaged are. This tends to be a last resort because it is a difficult (metabolically) and drastic change
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Denervation super-sensitivity
This is when intact cells become hyper-sensitive to stimulation so larger results are experienced from the same amount of neurotransmitters
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Unmasking
Dormant synapses which were functionally blocked (e.g. as a result of under-stimulation) are “revealed” when input increases
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Crowding hypothesis
A brain which is damaged congenitally, can often initially compensate with maximal rewiring, however this individual would struggle significantly more if there was more damage, or alternatively they would have difficulties adapting to acquire further mental skills (e.g. onset of school). It’s as if they “ran out of wiring”
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NREM sleep
Non-REM sleep: slow-wave sleep (stages 1-4) and where plasticity and neural change occur.
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REM sleep
Rapid Eye Movement sleep: paradoxical and desynchronised. It is where dreams and emotional processing occur.
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Stage 2
Slightly deeper sleep, breathing and heart rate slow. Neural activity is characterised by theta waves
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Stage 3
Deep sleep where theta waves begin to turn into delta waves
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Stage 4
Very deep sleep where healing and repair occur, this is also where sleep-walking occurs
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Neurons
Specialised cells in the brain and NS that transmit electrical impulses, enabling thought, speech, movement etc.
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Spatial summation
EPSPs are generated from many different pre-synaptic neurons, their effects are combined and summated.
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Temporal summation
High frequency action potentials of a single pre-synaptic neuron.
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Process of cortisol secretion
Hyp → CRH → Pit → ACTH → Ad C → Cortisol
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HPA axis
Second wave of fight or flight or chronic stress.
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Process of adrenaline secretion
Amygdala sends a distress signal to the hypothalamus Sympathetic NS is activated Bodily changes Adrenal medulla → adrenaline Adrenaline maintains these symptoms
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Visual information
Received as light energy in the photoreceptors in the retina, before being translated in the ganglion cells in the retina. It travels along the optic nerve as an impulse before being received in the thalamus (relay station). Then it is directed and interpreted in the visual cortex in the occipital lobe.
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Auditory information
Received in the cochlea in the inner ear, and is translated in the Organ of Corti. It travels along the auditory nerve and is first received in the brain stem (where basic decoding takes place), then the thalamus then the auditory cortex in the temporal lobe.
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Somatosensory and motor humunculus
Both cortices have the whole body represented, but it is represented contralaterally, upside down and not proportionally. The size of the body part on the cortex is due to the sizes of sensory receptors and muscle effectors, not the actual size of the body part.
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Broca’s area
Responsible for the production of language, found in the posterior portion of the left frontal lobe. (expressive aphasia)
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Arcuate fasiculus
Supporting evidence for language centres: this neural loop links both centres suggesting they work together.
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Global aphasia
All language capabilities are lost due to extensive damage.
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Dronkers et al, 2007
They used MRI scans and found that the damage Broca found was more extensive than initially concluded, so language may be more distributed.
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VJ case study
Epileptic convulsions led to bilateral hippocampal atrophy, most function was recovered but his episodic memory suffered.
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Localisation of function
The theory that particular regions of the brain are responsible for specific functions. It means that behaviours originate from specific, discrete regions.
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Hemispheric lateralisation
The theory that each hemisphere is specialised for distinct ways of processing and particular functions.
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Case study of JW
Found that while recognition of familiar others is specialised to the right hemisphere, the left hemisphere has a preference for self-recognition (to a very high degree of significance). Speaking about lateralisation too simply is a problem, but this provides evidence for it but in a more complex way.
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Case study of EB
He had his whole left hemisphere removed at 2.5 yrs and after intensive rehab was able to recover most of his language functions. This suggests that the brain is very able to adapt. However, he had a low IQ and systematic testing revealed difficulties with grammar which suggests that while the right hemisphere was able to create a left-like neural blueprint (copy what would have been on the left hemisphere), it was unable to fully take on the role of the left hemisphere.
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Plasticity
The brain’s ability to adapt in response to experience
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Congenital damage
Brain damage resulted from development so it was present at birth.
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Acquired damage
Brain damage results from later trauma or insult.
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Kennard Principle
Suggests that the younger the individual is when the damage occurs the better their chances of recovery. However, this is only true for acquired damage. For congenital damage, there was seen to be a negative relationship between a child’s IQ and their age.
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7x
Schneider found that individuals are this many times more likely to be disability-free after a moderate to severe brain injury if they have a college level education. He called this “cognitive reserve”.
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Circadian rhythms
Any bodily cycle that lasts about 24 hours, even in the absence of environmental stimuli
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Free-running
Any biological rhythm that continues in the absence of environmental stimuli.
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Suprachiasmatic nucleus
Region in the brain which sits close to the hypothalamus. It is entrained (synchronised to stimuli) by light signals and then it sends signals to the peripheral oscillators.
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Stage 1 sleep
Light sleep where we feel drowsy and muscle activity slows down: the brain has alpha waves
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Endogenous pacemakers
Mechanisms within the body that govern bodily rhythms (SCN)
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Exogenous zeitgebers
External, environmental cues that regulate the body clock (light)
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Stimulus
Anything internal or external that brings about a change
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Response
Any reaction in the presence of the stimulus
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Reinforcement
The process by which a response is strengthened
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Classical conditioning
Learning through association: a learning process that occurs when two stimuli are repeatedly paired so a response that is at first elicited by the second stimulus is eventually elicited by the first stimulus alone.
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UCS
Unconditioned stimuli - stimuli that automatically triggers a response
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UCR
Unconditioned response - an unlearned, natural response to the UCS
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NS
Neutral stimulus - stimulus that does not elicit a response prior to conditioning
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CS
Conditioned stimuli - after association with the UCS, elicits a certain response
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CR
Conditioned response - the learned response to a previously neutral response .
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Operant conditioning
Learning through reinforcement or punishment
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Positive punishment
Adding an undesirable stimulus to stop or decrease a behavior
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Negative punishment
The removal of a stimulus to decrease the probability of a behavior's recurring
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Positive reinforcement
Adding a desirable stimulus to increase the frequency of a desired behaviour
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Negative reinforcement
Increasing behaviors by stopping or reducing negative stimuli, such as shock. A negative reinforcer is any stimulus that, when removed after a response, strengthens the response. (Note: negative reinforcement is not punishment.)
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Social learning
Learning through the observation of others and imitating the behaviours that appear to be rewarded.
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Modelling
Learning through the observation of other people (models) which may lead to imitation (repetition) of behaviour.
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Mediational process
ATTENTION is payed to the model RETENTION allows an individual to copy the observed behaviour at a later date MOTOR REPRODUCTION is the imitation of the behaviour (has to be physically possible) MOTIVATION can result from direct or indirect (vicarious) reinforcement or punishment
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Behavioural genetics
The study of whether a trait runs in families. If it occurs more frequently in those who are related, we assume the trait has a genetic component.
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Molecular genetics
The study of gene variants in the DNA sequence that co-occur with disorders or diseases
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Genotype
The inherited genetic material that provides the code/instructions for the living organism
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Phenotype
How the genetically inherited code is expressed - the resulting, often observable characteristic - which is a result of the interaction between the genotype and the environment
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Adaptive
Traits which are useful and are likely to confer increased survival or reproductive success on the carrier are considered adaptive
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Traits
Characteristics, or features or behaviours
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Evolution
Change over successive generations of the genetic make-up of a particular population.
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Natural selection
The process by which inherited characteristics that enhance an individual's reproductive success, or 'fitness' are passed on to the next generation and so become more widespread in the gene pool
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Concordance
The degree of 'agreement' or sharing of trait between related individuals
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Monozygotic
Identical twins - share 100% of their DNA
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Dizygotic
Non-identical twins - share on average 50% of their DNA
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Heredity
The passing on of physical or mental characteristics genetically from one generation to another