DOSAGE-chap-8-Tablets

Tablet

Solid dosage form usually prepared with pharmaceutical excipients, varying in size and characteristics for specific uses.

Compressed Tablets

Tablets prepared by compression containing pharmaceutical excipients for oral, buccal, sublingual, or vaginal administration.

Diluents

Fillers that add necessary bulk to a formulation to prepare tablets of desired size.

Binders

Adhesives that promote adhesion of particles in a formulation to maintain the integrity of the final tablet.

Disintegrants

Agents that promote the breakup of tablets into smaller particles for ready drug availability after administration.

Antiadherents

Substances that minimize stickiness of ingredients to prevent clumping during tablet formation.

Multiple Compressed Tablets

Tablets prepared by more than one compression, forming layered or core-shell structures for effects like staged drug release.

Sugarcoated Tablets

Tablets coated with a sugar solution for taste masking, that may increase size, weight, and cost.

Film-coated Tablets

Tablets coated with a thin polymer film that dissolves in the gastrointestinal tract, offering advantages over sugarcoating.

Enteric-coated Tablets

Tablets designed to dissolve in the intestine rather than the stomach, preventing drug degradation by gastric acid.

Buccal Tablets

Flat, oval tablets intended to dissolve in the buccal pouch for absorption through oral mucosa.

Sublingual Tablets

Tablets designed to be placed under the tongue for rapid drug absorption.

Chewable Tablets

Tablets designed for smooth disintegration when chewed, often flavored for easier swallowing.

Effervescent Tablets

Tablets that release gas when in contact with water, enhancing dissolution of the active drug.

Molded Tablets

Soft, soluble tablets prepared by molding rather than compression for rapid dissolution.

Tablet Triturates

Small, molded tablets containing potent drugs, designed for rapid dissolution.

Hypodermic Tablets

No longer used; previously dissolved in a vehicle for injection; eliminated due to sterilization challenges.

Immediate-Release Tablets

Tablets that disintegrate and release medication without special rate-controlling features.

Extended-Release Tablets

Tablets that release their medication over an extended period in a controlled manner.

Vaginal Tablets

Tablets designed for insertion into the vagina for local effects, often containing antibacterials or antifungals.

Quality Standards in Tablets

Specifications relating to weight, disintegration, dissolution, and other physical characteristics that tablets must meet.

Friability

The tendency of tablets to crumble during handling, transportation, or aging.

Dissolution

The process by which a tablet disintegrates and releases the drug into solution for absorption.

Fluid Bed Granulation

A continuous process involving pre-blending, granulating, and drying to produce tablet ingredients.

Tablet Coating

The application of a protective layer to tablets to prevent degradation, mask taste, or provide controlled release.

Sugarcoating

A method that involves multiple layers of sugar syrup to coat tablets, making them larger and more aesthetically pleasing.

Film Coating

A process that applies a thin, skin-tight plastic-like layer to tablets, enhancing stability and intake ease.

Glidants

Substances added to improve the flow properties of powders in tablet formulations.

Pills

Small, round dosage forms that are medicinal agents intended for oral administration, usually made by molding.

Lozenges

Designed to dissolve slowly in the mouth, containing one or more active drugs along with a flavored base.

Pellets

Small, solid particles or beads manufactured for controlled release of active ingredients.

Bolus Tablets

Large, elongated tablets intended for administration to large animals.

What are enteric-coated tablets designed for?

They are designed to dissolve in the intestine rather than the stomach.

What is the main purpose of binders in tablet formulations?

Binders act as adhesives that promote adhesion of particles in a formulation.

How do effervescent tablets enhance drug dissolution?

They release gas when in contact with water, increasing the speed of dissolution.

What distinguishes multiple compressed tablets?

They are prepared by more than one compression, creating layered or core-shell structures.

What is the role of disintegrants in tablets?

Disintegrants promote the breakup of tablets into smaller particles for better drug availability.

What are buccal tablets used for?

They are intended to dissolve in the buccal pouch for absorption through the oral mucosa.

What defines immediate-release tablets?

They disintegrate and release medication without any special rate-controlling features.

What is the purpose of using glidants in tablet formulations?

Glidants improve the flow properties of powders during tablet production.

How do film-coated tablets differ from sugarcoated tablets?

Film-coated tablets have a thin polymer film that dissolves in the gastrointestinal tract.

What are the quality standards in tablets based on?

They relate to criteria such as weight, disintegration, dissolution, and other physical characteristics.

What are the characteristics of molded tablets?

Molded tablets are soft, soluble tablets prepared by molding rather than compression, allowing for rapid dissolution.

What is the function of antiadherents in tablet formulation?

Antiadherents minimize stickiness of ingredients to prevent clumping during tablet formation.

What defines chewable tablets?

Chewable tablets are designed for smooth disintegration when chewed and often flavored for easier swallowing.

How do extended-release tablets work?

Extended-release tablets release their medication over an extended period in a controlled manner.

What are the common uses of vaginal tablets?

Vaginal tablets are designed for insertion into the vagina for local effects, commonly containing antibacterials or antifungals.

What is the role of fluid bed granulation in tablet production?

Fluid bed granulation is a continuous process involving pre-blending, granulating, and drying to create tablet ingredients.

What are the advantages of using film coating over sugarcoating?

Film coating enhances stability, allows for easier intake, and is typically thinner than sugarcoating.

What are immediate-release tablets primarily used for?

Immediate-release tablets are used for rapid release of medication without special rate-controlling features.

What is the importance of friability testing?

Friability testing assesses the tendency of tablets to crumble during handling, transportation, or aging.

What are the key components of tablet coating?

Tablet coating usually involves the application of a protective layer to prevent degradation, mask taste, or provide controlled release.

What is a tablet?

A solid dosage form prepared with pharmaceutical excipients, varying in size and characteristics for specific uses.

What are compressed tablets?

Tablets prepared by compression containing pharmaceutical excipients for oral, buccal, sublingual, or vaginal administration.

What are diluents?

Fillers that add necessary bulk to a formulation to prepare tablets of desired size.

What role do binders play in tablet formulations?

Adhesives that promote adhesion of particles in a formulation to maintain the integrity of the final tablet.

What are disintegrants?

Agents that promote the breakup of tablets into smaller particles for ready drug availability after administration.

What are antiadherents used for?

Substances that minimize stickiness of ingredients to prevent clumping during tablet formation.

What are multiple compressed tablets?

Tablets prepared by more than one compression, forming layered or core-shell structures.

What is the purpose of sugarcoated tablets?

Tablets coated with a sugar solution for taste masking that may increase size, weight, and cost.

What are film-coated tablets?

Tablets coated with a thin polymer film that dissolves in the gastrointestinal tract.

What characterizes enteric-coated tablets?

Designed to dissolve in the intestine rather than the stomach, preventing drug degradation.

What are buccal tablets?

Flat, oval tablets intended to dissolve in the buccal pouch for absorption through oral mucosa.

What purpose do sublingual tablets serve?

Tablets designed to be placed under the tongue for rapid drug absorption.

What are chewable tablets?

Tablets designed for smooth disintegration when chewed, often flavored for easier swallowing.

What differentiates effervescent tablets?

Tablets that release gas when in contact with water, enhancing dissolution of the active drug.

What defines molded tablets?

Soft, soluble tablets prepared by molding rather than compression for rapid dissolution.

What are tablet triturates?

Small, molded tablets containing potent drugs, designed for rapid dissolution.

What are hypodermic tablets?

No longer used; previously dissolved in a vehicle for injection, eliminated due to sterilization challenges.

What are immediate-release tablets?

Tablets that disintegrate and release medication without special rate-controlling features.

What are extended-release tablets?

Tablets that release their medication over an extended period in a controlled manner.

What are vaginal tablets?

Tablets designed for insertion into the vagina for local effects, often containing antibacterials or antifungals.

What are quality standards in tablets?

Specifications relating to weight, disintegration, dissolution, and other physical characteristics that tablets must meet.

What is friability in relation to tablets?

The tendency of tablets to crumble during handling, transportation, or aging.

What is dissolution?

The process by which a tablet disintegrates and releases the drug into solution for absorption.

What is fluid bed granulation?

A continuous process involving pre-blending, granulating, and drying to produce tablet ingredients.

What is tablet coating?

The application of a protective layer to tablets to prevent degradation, mask taste, or provide controlled release.

What is sugarcoating?

A method that involves multiple layers of sugar syrup to coat tablets, making them larger and more aesthetically pleasing.

What is film coating?

A process that applies a thin, skin-tight plastic-like layer to tablets, enhancing stability and intake ease.

What are glidants?

Substances added to improve the flow properties of powders in tablet formulations.

What are pills?

Small, round dosage forms that are medicinal agents intended for oral administration, usually made by molding.

What are lozenges?

Designed to dissolve slowly in the mouth, containing one or more active drugs along with a flavored base.

What are pellets?

Small, solid particles or beads manufactured for controlled release of active ingredients.

What are bolus tablets?

Large, elongated tablets intended for administration to large animals.

What is the benefit of enteric-coatings?

They protect the active ingredients from gastric acid and ensure release in the intestine.

What is the definition of controlled release?

A formulation method that allows a drug to be released over a specific period in a regulated manner.

What is the significance of tablet hardness?

It affects the tablet's ability to withstand mechanical stresses during manufacturing and handling.

What are the aesthetic purposes of sugarcoating?

Sugarcoating makes tablets visually appealing and helps mask unpleasant tastes.

What is the role of lubricants in tablet formulation?

Lubricants reduce friction during tablet processing, preventing sticking to the machinery.

How does tablet thickness affect production?

Tablet thickness can influence dissolution rates and the physical integrity of the dosage form.

What is the impact of humidity on tablets?

High humidity can lead to moisture uptake, affecting stability and dissolving characteristics.

What is the purpose of a tablet's dissolution profile?

It helps predict how the drug will be released and absorbed in the body following administration.

What factors influence tablet disintegration time?

Composition, manufacturing process, and environmental conditions can all affect disintegration time.

What is a core tablet?

The inner tablet that contains the medication, sometimes coated for controlled release or taste masking.

What is a rapid-dissolving tablet?

A tablet designed to dissolve quickly in the mouth without the need for water.

What are effervescent granules?

Granules that release carbon dioxide when dissolved in water, aiding in rapid dissolution.

What is a reservoir tablet?

A type of extended-release tablet where the drug is contained in a core surrounded by a rate-controlling membrane.