PHAR 641: Pathophysiology of Skin Disorders

What are the types of flat leasions?

-Macule

-Patch

-Erythema

-Exanthem

-Cellulitis

What is a macule?

A flat area of skin with abnormal color

What is a patch?

A flat area of skin with different color from surrounding tissue

What is an erythema?

Temporary redness of skin

What is an exanthem?

Widespread skin eruption or rash

What is cellulitis?

Inflammation of cellular tissue of subcutaneous layers

What are the types of depressed lesions?

-Ulcer

-Erosion

-Fissure

-Striae

What is an ulcer?

Results form loss of epidermis layer and part of the dermis layer

What is an erosion?

Shallow lesion due to loss of epidermal epithelium

What is a fissure?

A deep, narrow crack in the epidermidis

What is a striae?

Stretch mark

What are the types of raised lesions?

-Cyst

-Papule

-Plaque

-Maculopapular

-Urticaria

What is a cyst?

Closed cavity or sac containing fluids or semi-solid exudate

What is a papule?

A solid, elevated lesion

What is a plaque?

A group of small papules

What is a maculopapular?

Rash consisting of macules and papules

What is urticaria?

Raised, itchy bumps

-Mast cells to release inflammatory cytokines

What are the fluid filled lesions?

-Vesicle

-Bulla

-Abscess

-Furuncle

-Pustule

What is a vesicle?

Fluid containing, epidermal elevation

What is a bulla?

fluid-filled vesicle

What is an abscess?

Collection of pus

What is a furuncle?

A boil

-Painful, red, without pus

What is a pustule?

Small elevation of the skin due to accumulation of pus in a sebaceous follicle

What are the purpura/vascular lesions?

-Petechiae

-Purpura

What are petechiae?

Macules; due to broken capillary blood vessels

What are the types of surface changes?

-Scale

-Crusts

-Excoriation

-Lichenification

-Xerosis

-exfoliation

-Ichthyosiform