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what are quiescent cells?
inactive but not dead
what are necrotic cells?
cells that have undergone accidental death due to unexpected damage
what are apoptotic cells?
cells that have undergone programmed cell death
what triggers extrinsic apoptosis?
killer lymphocyte binds to receptors on the cell
what triggers intrinsic apoptosis?
release of cytochrome c from the mitochondria within the cell
how can improperly folded proteins cause human disease?
deposit protein aggregates called amyloid fibrils cause amyloidosis. soluble proteins are converted to insoluble fibrils in beta sheets. abnormal protein pulls other correctly-folded proteins into incorrect form.