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What is homeostasis
The regulation of the internal conditions of a cell or organism to maintain optimum conditions for function in response to internal and external changes
What does homeostasis maintain optimal conditions for?
Enzyme action
All cell functions
Why do conditions in your body need to be kept steady?
So that your cells can have the right conditions to function properly
Give three examples of controlling conditions in the body
blood glucose concentration
body temperature
water levels
What type of control systems are these?
Automatic
What might these control systems involve?
Nervous responses or chemical responses
What do all control systems include?
Receptors
Effectors
Coordination centres
What are receptors?
Cells which detect stimuli
What are stimuli?
Changes in the environment
What do coordination centres do?
Receive and process information from receptors
Examples of coordination centres
brain
spinal chord
pancreas
What are effectors?
Muscles or glands which bring about responses which restore optimum levels
What does the nervous system enable humans to do?
React to their surroundings and coordinate their behaviour
How is information relayed in the nervous system?
Information from receptors passes along cells (neurones) as electrical impulses to the central nervous system (CNS)
The CNS is the brain and spinal cord
The CNS coordinates the response of effectors which may be muscles contracting or glands secreting hormones
What does the central nervous system (CNS) consist of?
In vertebrates, only the brain and spinal cord
How is the CNS connected to the body in mammals?
By sensory neurons and motor neurons
What are sensory neurons?
The neurons that carry information as electrical impulses from the receptors to the CNS
What are motor neurons?
The neurons that carry information as electrical impulses from the CNS to effectors
What is the order of events for a reaction to a stimulus in the nervous system?
stimulus > receptor > coordinator > effector > response
What is a synapse?
The junction between two neurons
What is the gap in a synapse called?
A synaptic cleft
How do synapses work?
When an impulse reaches the end of the neuron, a chemical (neurotransmitter) is released
The neurotransmitters diffuse to the next neuron, triggering an electrical impulse to begin
What is a reflex?
A rapid, automatic response to certain stimuli that don’t involve the conscious part of the brain
Why do we have reflexes?
To prevent the chance of being injured
What is a reflex arc?
The passage of information in a reflex (from receptor to effector)
How is the pathway of a reflex arc different from the usual response to stimuli?
The impulse does not pass through the conscious areas of the brain
Describe a reflex arc
Receptor detects stimulus
Electrical impulses are sent along a sensory neuron
In the CNS (spinal cord/ brain) the impulse passes to a relay neuron
Impulses are then sent along the motor neuron
There is a synapse between all of these neurons where the neurotransmitters cross the gap by diffusion
The impulse reaches an effector resulting in the appropriate response
Give 2 examples of reflex arcs
pupils getting smaller to avoid damage from bright lights
moving your hand from a hot surface to prevent damage
What does the brain do?
Control complex behaviour
Describe the structure of the brain
It is made of billions of interconnected neurons and has different regions that carry out different functions
What are the three components of the brain?
Cerebral cortex
Cerebellum
Medulla
What does the cerebral cortex control?
(cereal and MILC)
Memory
Intelligence
Language
Consciousness
What part of the brain is the cerebral cortex?
The outer part
What does the cerebellum control?
Fine movement of muscles
What part of the brain is the cerebellum?
The rounded structure towards the bottom/ back
What does the medulla control?
Unconscious actions like breathing and heart rate
What part of the brain is the medulla found in?
The brain stem in front of the cerebellum
Why is it difficult to investigate brain function and treating brain damage and disease?
It is complex and delicate
It is easily damaged
Drugs given to treat diseases cannot always reach the brain because of the membranes that surround it
It is not fully understood which part of the brain does
What have neuroscientists been able to do?
Map the regions of the brain to particular functions by:
studying patients with brain damage
electrically stimulating different parts of the brain
using MRI scanning techniques
What is the eye?
A sense organ containing receptors sensitive to light intensity and colour
What is the eye adapted for?
Accomodation (allowing the eye to change its shape in order to focus on near or distant objects)
Adaption to dim light
Parts of the eye (7)
retina
optic nerve
sclera
cornea
iris
ciliary muscles
suspensory ligaments
What is the retina?
A layer of light sensitive cells found at the back of the eye
What does the retina do
When light hits it, the cells are stimulated
Impulses are sent to the brain, which interprets the information to create an image
What is the optic nerve?
A nerve that leaves the eye and leads to the brain
What does the optic nerve do?
Carries the impulses from the retina to the brain to create an image
What is the sclera?
The white outer layer which supports the structures inside the eye
What is an adaptation of the sclera?
It is strong to prevent some damage to the eye
What is the cornea?
The see-through layer at the front of the eye
What does the cornea do?
It allows light through
The curved surface bends and focuses light onto the retina
What is the iris?
The muscles that surround the pupil
What do the iris muscles do?
Contract or relax to alter the size of the pupil
What do the iris muscles do in bright light?
Circular muscles contract
Radial muscles relax to make the pupil smaller
this avoids damage to the retina
What do the iris muscles do in dim light?
Circular muscles relax
Radial muscles contract to make the pupil larger
so more light can enter to create a better image
What do the ciliary muscles and suspensory ligaments do?
Hold the lens in place
Control its shape
What is accomodation?
The process of changing the shape of the lens to focus on near or distant objects
How does the eye focus on a near object?
the ciliary muscles contract
the suspensory ligaments loosen
the lens is then thicker and refracts light rays strongly
How does the eye focus on a distant object?
the ciliary muscles relax
the suspensory ligaments are pulled tight
the lens is then pulled thin and only slightly refracts light rays
When do eye defects occur?
When light cannot focus on the retina
What are two common defects of the eyes?
myopia (short sightedness)
hyperopia (long sightedness)
What is myopia?
When the lens is too curved, so distant objects appear blurry
What is hyperopia?
When the lens is too flat, so it cannot refract light enough
How are these eye defects treated generally?
With spectacle lenses which refract the light rays so they do focus on the retina
What new technologies are there to correct myopia and hyperopia?
hard and soft contact lenses
laser surgery to change the shape of the cornea
a replacement lens in the eye
How is body temperature monitored and controlled?
By the thermoregulatory centre in the brain
What does the thermoregulatory centre contain?
Receptors sensitive to the temperature of the blood
What part does skin play in the control of body temperature?
It skin contains temperature receptors and sends nervous impulses to the thermoregulatory centre
What is human body temperature?
37.5 degrees celsius
What happens if your body temperature is too high?
Blood vessels dilate (vasodilation)
Sweat is produced from the sweat glands
What does vasodilation mean?
More blood flows closer to the surface of the skin, resulting in increased energy transfer from the body
What does sweat do?
Evaporates from skin surface resulting in increased energy transfer away from body
What happens if your body temperature is too low?
Blood vessels constrict (vasoconstriction)
Sweating stops
Skeletal muscles contract (shiver)
Hairs stand on end
What does vasoconstriction mean?
Blood does not flow so close to the surface, resulting in less heat lost
What does shivering do?
Generate heat from respiration
What do hairs standing on end do?
Create an insulating layer, trapping warm air
What are the two communication systems of the human body?
the endocrine system
the nervous system
What is the endocrine system composed of?
glands which secrete chemicals called hormones directly into the bloodstream
the blood carries the hormone to a target organ where it produces an effect
What are hormones?
Chemical messenger made by the endocrine system which affects a specific target organ and is released and carried by the blood
What are hormones caarried in?
The blood plasma
How does the endocrine system compare to the nervous system
chemical messengers rather than nervous impulses
effects are slower
effects last longer
act more generally
Where is the pituitary gland?
The brain
What is the pituitary gland?
A ‘master gland’ which secretes several hormones into the blood in response to body conditions
These hormones in turn act on other glands to stimulate other hormones to be released to bring about effects
Why does your blood glucose level need to be kept within a certain limit?
Glucose is needed by cells for respiration
How can you increase blood glucose levels?
Eating foods that contain carbohydrates
What does the pancreas do?
Monitor and control blood glucose concentration
What happens if the blood glucose concentration is too high?
pancreas secretes hormone insulin
this causes glucose to move from blood into cells
in liver and muscle cells, excess glucose is converted to glycogen for storage
What happens if the blood glucose concentration is too low?
the pancreas secretes the hormone glucagon
this causes glycogen to be converted into glucose and released into the blood
What is Type 1 diabetes?
A disorder in which the pancreas fails to produce sufficient insulin
It is characterised by uncontrolled high blood glucose levels
It is normally treated with insulin injections
What is Type 2 diabetes?
When the body cells no longer respond to insulin produced by the pancreas
A carbohydrate controlled diet and an exercise regime are common treatments
What is a risk factor for Type 2 diabetes?
Obesity
What can high blood glucose be fatal? - osmosis
there will be water movement out of cells
dilute to concentrated solution of water
across partially permeable membrane
causes cells to shrink
What is negative feedback?
How your automatic control systems keep your internal environment stable
How your body decreases the level of something with negative feedback
Receptor detects a stimulus - level is too high
The coordination centre receives and processes the information, then organises a response
Effector produces a response which counteracts the change and restores the optimum - the level decreases
What is osmosis?
The net movement of water particles across a partially permeable membrane from an area of high water concentration (dilute) to an area of low water concentration (concentrated) down the concentration gradient
What happens if the water concentration of the blood increases?
Cells in the body take up water by osmosis
This is because the conc. of water in the blood is lower than the conc. in cells
Cells expand as they take up more water
They may burst
What happens if the water concentration of the blood decreases?
Cells lose water
Causing them to shrink
How does water leave the body?
Sweating
Via the lungs during exhalation
In urine - depending in the conc. of water in the blood
What leaves the body in sweat?
Water
Urea
Ions
Is there control over the water, ions and urea that leaves the body via the lungs and sweat?
No
What happens if body cells lose or gain too much water?
They do not function efficiently