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What is Science?
method for studying the natural world
deductive reasoning
reasoning in which a conclusion is reached by stating a general principle and then applying that principle to a specific case (The sun rises every morning; therefore, the sun will rise on Tuesday morning.)
inductive reasoning
A type of logic in which generalizations are based on a large number of specific observations.
hypothesis-driven science
the process of scientific inquiry that uses the steps of the scientific method to answer questions about nature
Characteristics of living things
reproduce, grow, respond, cells, DNA, energy
Levels of Biological Organization
atom, molecule, cell, tissue, organ, organ system, organism, population, community, ecosystem, biosphere
A Mysterious Orange Cat Talks Openly Onstage & Sings Opera
taxonomic ranks in order
Domain, Kingdom, Phylum, Class, Order, Family, Genus, Species
Eukaryote
-all have nuclei
-single or multi celled
-plants
-fungi
-animals
-protisis
Cohesion
Attraction between molecules of the same substance
Adhesion
An attraction between molecules of different substances
amphipathic molecules
containing hydrophobic and hydrophilic regions
Hydrophobic
Water fearing (Hydro=NO)
Hydrophilic
water loving
Acid
A substance that increases the hydrogen ion concentration of a solution.
Base
A substance that decreases the hydrogen ion concentration in a solution.
cell theory
-all organisms have cells
-smallest living things
-pre-existing
hydroxyl group
-carbohydrates
-protiens
-nucelic acids
-lipids
carbonyl group
-carbohydrates
-nucelic acids
carboxyl group
-protiens
-lipids
amino group
-protiens
-nucelic acids
sulfhydryl group
protiens
phosphate group
nucleic acids
methyl group
protiens
Carbohydrates
energy storage, structural support
protiens
enzymes, structural support
nucelic acids
storage and transfer of genetic information
Lipids
energy storage, membrane structure, cell communication
Monosaccharides
glucose, fructose, galactose
disaccharides
sucrose, lactose, maltose
Polysaccharides
many sugars
amino acid sequence
The order of the amino acid subunits in a protein chain. Sometimes called the primary structure of a protein.
polypeptide secondary structure
polypeptide tertiary structure
polypeptide quarternary structure
Nucleoid
A dense region of DNA in a prokaryotic cell.
Cytoplasm
A jellylike fluid inside the cell in which the organelles are suspended
Ribosomes
Makes proteins
plasma membrane
phospholipid bylayer
prokaryotic cells
do not have a nucleus or other membrane-bound organelles
endomembrane system
A network of membranes inside and around a eukaryotic cell, related either through direct physical contact or by the transfer of membranous vesicles.
Rough ER
That portion of the endoplasmic reticulum studded with ribosomes.
Smooth ER
That portion of the endoplasmic reticulum that is free of ribosomes.
Golgi apparatus
A system of membranes that modifies and packages proteins for export by the cell
Lysosomes
An organelle containing digestive enzymes
Vessicle
A small, membrane-bound sac that transports subjects in and out of cells.
Vacuole
Cell organelle that stores materials such as water, salts, proteins, and carbohydrates
Mitcohondira
"powerhouse of the cell", produces ATP, has double membranes, contains own DNA, resemble bacteria
Chloroplast
An organelle found in plant and algae cells where photosynthesis occurs
Centrosome
A structure in animal cells containing centrioles from which the spindle fibers develop.
factors that reduce membrane fluidity
-temperature
-longer fattty acid chains
-saturated fatty acid chains
membrane protiens
transport by channel proteins
create a pore in the membrane
passive transport
the movement of substances across a cell membrane without the use of energy by the cell
active transport
Energy-requiring process that moves material across a cell membrane against a concentration difference
coupled transport
The movement of a substance against its electrochemical gradient (from lower to higher concentration, or from opposite charge to like charge) using the energy provided by the simultaneous movement of a different chemical down its electrochemical gradient.
Osmosis
Diffusion of water through a selectively permeable membrane
low to high
Diffusion
Movement of molecules from an area of higher concentration to an area of lower concentration.
Endocytosis
process by which a cell takes material into the cell by infolding of the cell membrane
Pinocytosis
Cell drinking
receptor-mediated endocytosis
binding of ligands to receptors triggers vesicle formation
Phagocytosis
Cell eating
Thermodynamics
The study of energy transformations that occur in a collection of matter.
Oxidation
loss of electrons
reduction
gain of electrons
redox reactions (oxidation-reduction reactions)
first law of thermodynamics
Energy can be transferred and transformed, but it cannot be created or destroyed.
second law of thermodynamics
Every energy transfer or transformation increases the entropy of the universe.
Gibbs free energy
H= enthalpy
T= temperature (K)
S= entropy
G= change in free energy
endergonic reaction
A non-spontaneous chemical reaction in which free energy is absorbed from the surroundings.
exergonic reaction
A spontaneous chemical reaction in which there is a net release of free energy.
activation energy
Energy needed to get a reaction started
catalyst
substance that speeds up the rate of a chemical reaction
Enzymes as biological catalysts
Each enzyme lowers the activation energy of the reaction it catalyses to speed up rate of reaction
active site
The part of an enzyme or antibody where the chemical reaction occurs.
catalytic cycle
factors that influence enzyme function
-temp
-pH
-regulatory
Anabolic
A process in which large molecules are built from small molecules
catabolic
A process in which large molecules are broken down
feedback inhibition
A method of metabolic control in which the end product of a metabolic pathway acts as an inhibitor of an enzyme within that pathway.
Adenosine Triphosphate (ATP)
compound used by cells to store and release energy
atp cycle
autotrophs
Organisms that make their own food
Heterotroph
An organism that cannot make its own food.
cellular respiration
Process that releases energy by breaking down glucose and other food molecules in the presence of oxygen
anerobic respiration
Respiration that does not require oxygen
Glycolysis
the breakdown of glucose by enzymes, releasing energy and pyruvic acid.
pyruvate oxidation
Conversion of pyruvate to acetyl CoA and CO2 that occurs in the mitochondrial matrix in the presence of O2.
Krebs cycle
third stage of cellular respiration, in which pyruvic acid is broken down into carbon dioxide in a series of energy-extracting reactions
electron transport chain
A sequence of electron carrier molecules (membrane proteins) that shuttle electrons during the redox reactions that release energy used to make ATP.
ATP synthesis during glycolysis
-occurs via substrate-level phosphorylation
-direct transfer of Pi from another molecule (PEP) to ADP
pyruvate oxidation during aerobic respiration
-Occurs In:
-Mitochondrial matrix of eukaryotes
-Plasma membrane of prokaryotes
-Catalyzed by pyruvate dehydrogenase
Acetyl CoA+Oxaloacetate-->Citrate
citrate synthase
Citrate rearrangement and decarboxylation
second step in krebs cycle
Regeneration of Oxaloacetate
A water molecule is added forming Malate, which is then oxidized to produce an NADH molecule. Forms oxaloacetate and the Krebs cycle is ready to repeat again
aerobic respiration
-one glucose molecule has been oxidized to
6CO2, 4 ATP, 10 NADH, 2 FADH2
electron transport chain
allows for the stepwise extraction of energy as electrons are passed from component to the next
ETC components
-4 protein complexes I, II, III, IV
-additional protein components: coenzyme Q and cytochrome C
Chemiosmosis
A process for synthesizing ATP using the energy of an electrochemical gradient and the ATP synthase enzyme.
anaerobic respiration
-inorganic molecules used as final e- acceptor
-many prokaryotes use sulfur, carbon dioxide or even inorganic metals
-free energy relseased and ATP is less
Fermentation
-glycolysis is only source of ATP
- use of organic molecules as final e- acceptor
-redeuces organic molecs. to regenerate NAD+