glucagon

what is the number of amino acids in the glucagon chain

• 31 amino acids

what type of hormone is glucagon

peptide hormone

how does glucagon act

• acts by stimulation of a cell surface GPCR

what does glucagon increase

• increases cAMP

• G alpha s 

when is glucagon secreted

• during times of fasting (between meals)

• from alpha-cells of the islets of langerhans

• decreased glucose

• increased secretion

what is the major target organ of glucagont

• the liver 

• secreted into the hepatic portal vein

what does glucagon promote

the breakdown of energy stores, raising the level of energy sources in the blood

glucagon effects on carbohydrate metabolism

• increased blood sugar

• increased glycogenolysis 

• decreased glycogenesis 

• increased gluconeogenesis 

glucagon effects on fat metabolism

• increased levels of fatty acids in blood

• increased lipolysis 

• decreased triglyceride synthesis