ID Lecture 63: Antimicrobial Stewardship | Quizlet

Why is antimicrobial stewardship so important?

Improves patient outcomes while decreasing toxicity, antibiotic resistance, C. diff infections, and cost

What is antimicrobial stewardship?

coordinated interventions designed to improve and measure the appropriate use of antibiotic regimens

What are the 5 "Rights" of antimicrobial stewardship?

Right Drug

Right Bug

Right Time

Right Dose

Right Duration

What are the core elements of antimicrobial stewardship?

Hospital Leadership Commitment

Accountability

Pharmacy Expertise

Action

Tracking

Reporting

Education

What is "The Art of De-Escalation"?

Streamlining empirical antibiotic therapy once more information becomes available

What is the "Front End" of antimicrobial stewardship?

provided at the point of prescribing

formulary restrictions and preathorizations

What is the "Back End" of antimicrobial stewardship?

after the antimicrobial has been prescribed

prospective feedback audits, de-escalation, dose optimization

What are the 3 C's of antimicrobial stewardship?

Choice

Change

Completion

Days of therapy (DOT)

tracking and reporting method that is the most accurate where dose is NOT a factor

Defined Daily Dose (DDD)

Tracking and reporting method that was created by the WHO that tracks the assumed average maintenace dose per day

What are the 3 measurements of antibiotic use?

Days of therapy

Defined daily dose

Antimicrobial purchases

How can all pharmacists be involved in antimicrobial stewardship?

Use antibiograms

Use your facility's treatment protocols

Look for opportunities to de-escalate broad spectrum antibiotics

Say no to double anaerobic coverage

IV to PO conversions