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Muscarinic acetylcholine receptor
A G protein-coupled receptor that responds to acetylcholine.
Pre-ganglionic neuron
A neuron that is long in the parasympathetic nervous system.
Post-ganglionic neuron
A neuron that is short in the parasympathetic nervous system.
Parasympathetic output
Confined to the medulla and sacral region.
Sympathetic output
Confined to the thoracic and lumbar regions.
M1-3 receptors
Mainly found in glands, heart, and smooth muscle.
M4 and M5 receptors
Mainly found in the central nervous system (CNS).
Odd-numbered muscarinic receptors
Coupled to Gq proteins.
Even-numbered muscarinic receptors
Coupled to Gi proteins.
Physiological effects of sympathetic system
Fright, flight, fight.
Physiological effects of parasympathetic system
Rest and digest.