440 Coagulation Factors
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15 Terms
I
Fibrinogen
Fibrinogen Group
Serves as substrate and fibrin precursor
II
Prothrombin
Vit K group
Becomes Protease and is Thrombin Precursor
III
TF
Cofactor for Extrinsic Xase
IV
Ca++
Cofactor for most reactions
V
Proaccelerin
Fibrinogen group
Cofactor for prothrombinase complex
VII
Proconvertin
Vit K group
Protease and Extrinsic Xase constituent
VIII
Antihemophilic
Fibrinogen group
Complexes w/ VWF
Also Intrinsic Xase cofactor
VWF
Synth by endothelial cells and megakaryocytes
Serves to stabilize circulating VIII and facilitate plt adhesion to the vessel wall
IX
Christmas Factor (Plasma thromboplastin component)
Vit K group
Protease in the Intrinsic Xase
X
Stuart Factor
Vit K group
Protease of the prothrombinase complex
XI
Plasma Thromboplastin Antecedent
Contact Group
Contact Factor
XII
Hageman
Contact Group
Activates fibrinolytic and complement systems as well
XIII
Fibrin-Stabilizing
Fibrinogen group
Transglutaminase that stabilizes fibrin
HK
Fitzgerald
Contact group
Cofactor w PK and XI; contact factor
PK
Fletcher
Contact Group
Contact factor w HK in vitro
Note 
Flashcards (30)