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Asexual Reproduction
Process by which one organism produces genetically identical offspring without gametes or fertilization.
Binary Fission
DNA replicates and a septum forms to divide the cell into two identical daughter cells (e.g., prokaryotes, mitochondria).
Budding
small bud forms on the parent, receives a copy of DNA, and detaches as a new organism (e.g., yeast, hydra).
Regeneration
Fragment of an organism grows into a new one or regenerates missing parts (e.g., planaria, hydra).
Parthenogenesis
Unfertilized egg develops into a viable organism; common in bees (haplodiploidy: males haploid, females diploid)
Spermatogenesis
Formation of haploid sperm cells (spermatozoa) from diploid germ cells (spermatogonia) via meiosis.
Spermiogenesis
Final stage of spermatogenesis where spermatids mature into spermatozoa.
Sperm Structure
Head (nucleus + acrosome), midpiece (mitochondria for ATP), tail (flagellum for motility).
Seminal Vesicles
Produce fructose (energy), prostaglandins (urethral contractions), and mucus (lubrication).
Prostate Gland
Secretes alkaline fluid to neutralize uterine acidity.
Bulbourethral (Cowper’s) Glands
Produce viscous mucus that lubricates and cleans the urethra.
FSH (Follicle-Stimulating Hormone)
Stimulates sperm production in seminiferous tubules by activating Sertoli cells.
Sertoli Cells
Nourish developing sperm and secrete inhibin for negative feedback on FSH.
LH (Luteinizing Hormone)
Stimulates Leydig cells to produce testosterone.
Leydig Cells
Produce testosterone for sperm maturation and male secondary sex traits.
Testosterone
Hormone responsible for sperm development and male secondary characteristics.
Oogenesis
Production of a haploid ovum (egg) from diploid oogonia via meiosis with unequal cytoplasmic divisions.
Ovary
Produces ova (eggs) and female hormones.
Fimbriae
Finger-like projections that receive released eggs from the ovary.
Oviduct (Fallopian Tube)
Transports eggs from ovary to uterus; site of fertilization.
Uterus
Muscular organ with three layers — perimetrium (outer), myometrium (muscular), endometrium (inner epithelial) — supports embryo implantation.
Cervix
Narrow passage between uterus and vagina.
Vagina
Muscular canal leading to the outside of the body; site of sperm entry and birth canal.
Follicle
Fluid-filled sac in ovary containing an immature oocyte (arrested in prophase I); later forms corpus luteum.
Corpus Luteum
Structure formed after ovulation that secretes progesterone and estrogen to maintain the endometrium
FSH (Female)
Stimulates follicle growth and estrogen production.
LH (Female)
Triggers ovulation and corpus luteum formation.
Estrogen
Thickens endometrium and develops female secondary sex traits.
Progesterone
Maintains the endometrium and supports pregnancy.
GnRH (Gonadotropin-Releasing Hormone)
Released by hypothalamus to stimulate FSH and LH release from pituitary.
Positive Feedback
Enhances a biological process (e.g., oxytocin during childbirth, prolactin during lactation).
Positive Feedback
inhibits biological pathways (e.g., estrogen and progesterone suppress FSH/LH).
Negative Feedback
Inhibits biological pathways (e.g., estrogen and progesterone suppress FSH/LH).
Follicular Phase
FSH stimulates follicle growth and estrogen production; endometrium thickens.
Ovulation
LH surge releases mature egg from Graafian follicle.
Luteal Phase
Corpus luteum secretes estrogen and progesterone to maintain the endometrium.
hCG (Human Chorionic Gonadotropin)
Hormone from placenta that maintains corpus luteum and endometrial lining during early pregnancy.
Fertilization
Fusion of haploid sperm and egg to form a diploid zygote
Capacitation
Final sperm maturation in the female reproductive tract; increases calcium permeability for hyperactivity.
Acrosomal Reaction
Sperm releases enzymes to penetrate zona pellucida (ZP3 protein) and fuse with egg membrane.
Polyspermy Block
Prevents multiple sperm from fertilizing one egg
Fast Block
Membrane depolarization preventing other sperm entry.
Slow Block
Cortical reaction forming fertilization envelope via calcium release.
Completion of Meiosis II
Triggered in the oocyte after sperm entry, forming mature ovum and polar bodies.
Monozygotic Twins
Identical twins formed from a single fertilized egg that splits.
Dizygotic Twins
Fraternal twins formed from two separate fertilized eggs
Cleavage
Rapid mitotic divisions of the zygote without overall growth, forming blastomeres.
Blastomeres
Smaller cells produced during cleavage.
Axis of Cleavage
Direction of cell division; spiral (protostomes) or radial (deuterostomes).
Regulative (Indeterminate) Cleavage
Cells can form complete embryos (deuterostomes)
Mosaic (Determinate) Cleavage
Cells have predetermined fates (protostomes).
Morula
Solid ball of blastomeres
Blastula
Hollow sphere with fluid-filled center (blastocoel).
Blastocyst
Differentiated blastula that implants into uterine wall.
Gastrulation
Formation of three germ layers: ectoderm, mesoderm, and endoderm.
Blastopore
Opening that forms during gastrulation; becomes mouth (protostomes) or anus (deuterostomes).
Archenteron
Primitive gut formed during gastrulation.
Ectoderm
Forms nervous system, sensory organs, skin, hair, nails, enamel, mammary/sweat glands, and adrenal medulla.
Mesoderm
Forms bones, muscles, cardiovascular system, gonads, spleen, notochord, and adrenal cortex.
Endoderm
Forms epithelial lining of digestive, respiratory, and excretory tracts; and organs like pancreas, liver, thyroid, parathyroid, and thymus.
Stem Cells
Undifferentiated cells capable of differentiating into specific cell types based on potency.
Neurulation
Formation of the nervous system; notochord induces ectoderm to form neural plate → neural tube (CNS).
Notochord
Mesodermal structure that signals ectodermal differentiation; forms basis of spinal column
Neural Crest Cells
Migrate to form teeth, facial cartilage, and pigmentation cells.
Somites
Mesodermal cells that form vertebrae and skeletal muscles.
Amnion
Innermost membrane secreting amniotic fluid to cushion embryo; found in reptiles, birds, and mammals (amniotes)
Chorion
Outermost layer; forms fetal side of placenta in mammals, or gas exchange surface in egg-layers.
Allantois
Sac for waste storage and gas exchange; forms umbilical cord and bladder in mammals
Yolk Sac
Provides early nutrients and first site of blood cell formation before placenta develops.
Embryonic Induction
Process by which organizer cells influence development of nearby cells.
Homeotic Genes
Determine structure placement and body plan; include HOX genes for anterior-posterior axis
Homeobox
Conserved DNA sequence in homeotic genes across species
Egg Cytoplasm Determinant
Uneven yolk distribution (animal and vegetal poles) influences cleavage pattern and cell fate.
Apoptosis
Programmed cell death essential for normal development and tissue sculpting.
Temperature-Dependent Sex Determination
Environmental temperature determines sex in some reptiles (e.g., turtles, crocodiles)