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Muscle Tissue Types
Skeletal, Cardiac, and Smooth muscle
Skeletal Muscle
Voluntary, striated, long cylindrical cells, multinucleated, attached to bones
Cardiac Muscle
Involuntary, striated, short branched cells, single nucleus, connected by intercalated discs
Smooth Muscle
Involuntary, nonstriated, spindle-shaped, single nucleus, found in walls of hollow organs
Voluntary Muscle
Muscle that is consciously controlled (skeletal muscle)
Involuntary Muscle
Muscle that contracts without conscious control (cardiac and smooth muscle)
Excitability
Ability to respond to electrical stimulation
Contractility
Ability of cells to shorten with force
Extensibility
Ability to be stretched beyond resting length
Elasticity
Ability to return to resting length after contraction or stretch
Functions of Skeletal Muscle
Movement, posture, support soft tissues, guard body openings, maintain temperature, store nutrients
Prefix 'myo-' or 'sarco-'
Means 'muscle'
Epimysium
Connective tissue surrounding entire muscle
Perimysium
Connective tissue surrounding fascicles (bundles of fibers)
Endomysium
Connective tissue surrounding each muscle fiber
Tendon
Bundle of collagen fibers attaching muscle to bone
Aponeurosis
Sheet of collagen fibers attaching muscle to bone
Myosatellite Cells
Stem cells that repair muscle damage
Skeletal Muscle Fiber
Long, cylindrical, multinucleated cell; also called a muscle fiber
Myofibril
Long protein cords inside muscle fibers that contract
Myofilaments
Actin and myosin proteins that make up myofibrils
Sarcolemma
Cell membrane of a muscle fiber
Sarcoplasm
Cytoplasm of a muscle fiber
T-tubule
Tube extending from sarcolemma into the muscle fiber; carries electrical impulses
Sarcoplasmic Reticulum (SR)
Stores and releases calcium ions (Ca²⁺)
Terminal Cisternae
Enlarged areas of SR next to T-tubules
Triad
One T-tubule + two terminal cisternae
Thick Filament
Made mostly of myosin
Myosin
Thick filament protein with heads that bind actin to produce contraction
Thin Filament
Made mostly of actin, plus tropomyosin and troponin
Actin
Protein in thin filament with active sites for myosin binding
Tropomyosin
Protein that covers actin’s active sites to prevent binding
Troponin
Protein that controls position of tropomyosin; binds to calcium
Sarcomere
Smallest functional (contractile) unit of muscle fiber
Z-Line (Z-disc)
Boundary between sarcomeres
A Band
Dark band; thick filaments (and overlapping thin filaments)
I Band
Light band; thin filaments only
M Line
Center of A band; holds thick filaments together
H Zone
Lighter area around M line; thick filaments only, no overlap
Zone of Overlap
Area where thick and thin filaments overlap
Striations
Alternating light (I) and dark (A) bands in skeletal and cardiac muscle
Muscle Hierarchy
Myofilaments → Sarcomere → Myofibril → Muscle Fiber → Fascicle → Muscle
Myoblasts
Embryonic cells that fuse to form muscle fibers
Voluntary Control
Muscle movement initiated by the nervous system (skeletal muscle)
Intercalated Discs
Specialized junctions in cardiac muscle that allow electrical connection between cells
Autorhythmic
Cardiac muscle’s ability to contract on its own without neural stimulation