Oestrogen and Transcription factors

type of biological molecule steroids are

lipids

how oestrogen passes through the phospholipid bilayer

by simple diffusion as it is lipid soluble

what oestrogen binds to

oestrogen receptors in target cells

what oestrogen bound to oestrogen receptors form

oestrogen- oestrogen receptor complexes

where oestrogen-oestrogen receptor complexes are formed

the cytoplasm

where oestrogen-oestrogen receptor complexes move to

the nucleus

what oestrogen-oestrogen receptor complexes bind to

promoter regions on DNA

what the binding of oestrogen-oestrogen receptor complexes activate on DNA

The binding of RNA polymerase and gene transcription

transcription factors

proteins which signal whether RNA polymerase should start transcribing a gene

how oestrogen allows transcription factors to activate transcription

changes the shape of their DNA binding site making it complementary in shape to the DNA

Activators

transcription factors which promote region of DNA for RNA polymerase to transcribe

Repressors

transcription factors which block RNA polymerase from binding to DNA preventing transcription

importance of transcription factors to the function of RNA polymerase

RNA polymerase can only bind to the DNA when transcription factors are present