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Dizziness, vertigo, & imbalance
Considered as top complaints in doctor’s offices, responsible for 5-8 million US visits yearly:
vestibular input
Which sense aids balance most?
locate position
Main job of balance system?
five sensory receptors
Membranous labyrinth contains what?
Superior canal
Which canal is vertical?
excitation
Kinocilium deflection causes?
inhibition
Stereocilia away from kinocilium causes…
endolymph flow
What bends the cupula?
hair cells
Crista ampullaris houses…
horizontal motion
Utricle primarily senses…
vertical motion
Saccule mainly detects…
calcium carbonate
Otoconia are composed of…
cochlear nerve
VIII nerve includes the
Opposite side
Horizontal VOR eyes move?
head movement
VOR stabilizes gaze during:
illusion of motion
Which best defines vertigo?
high blood pressure
Non-vestibular cause of imbalance?
illusion of motion
Vestibular system mismatch leads to
posterior canal
BPPV most commonly affects?
head position changes
What triggers BPPV episodes?
Autophony, conductive loss
SCD key symptom pair?
sound-induced vertigo
Tullio phenomenon involves?
oscillopsia
Classic vestibulotoxicity complaint?
Gentamicin
Ototoxic medication example?
Hearing loss in labyrinthitis
Neuritis versus labyrinthitis difference?
aging, head trauma
BPPV common precipitating factors?
world bouncing
Oscillopsia feels like?
Direction-changing nystagmus
Central balance signs include?
Vertigo, aural fullness, tinnitus
Meniere’s classic symptom trio?
motion sensitivity
Vestibular migraine may present with?
meniere’s disease
Endolymphatic hydrops relates to?
true
true/false: fall risk rises with age
hospitalization, fractures
Common outcomes after falls include:
Age-related unsteadiness
Presbyapondera mainly describes
vestibular cause
Primary vestibular question is:
angular acceleration
Semicircular canals primarily sense
linear acceleration
Otolith organs primarily sense
stabilize gaze
VOR purpose during head turns:
0.1 - 3 Hz
Vestibular sensitivity peak range
0.003 Hz range
Calorics mainly probe
Guide test choice
Case history first helps
Flag BPPV
Bedside screens can
eye movements
VNG/ENG primarily records
rotary chair
Best for bilateral hypofunction
saccule pathway
cVEMP predominantly assesses:
Dix-Hallpike
Which test triggers BPPV nystagmus?
Present low-threshold
cVEMP in SCD is typically…
reduced calorics
Bilateral vestibulotoxicity often shows…
vHIT
Which test reflects high-frequency VOR?
vestibular neuritis
Unilateral hypofunction suggests what condition?
inflammation resolved
Neuritis tests can appear normal when
false
true/false: calorics test high-frequency function
epley
Which maneuver treats posterior BPPV?
Unilateral caloric weakness
Meniere’s often shows these tests
reduced or absent
In Meniere’s, cVEMP may be…
highly variable
Vestibular migraine testing is typically…
Direction-changing nystagmus
Central disorders often show…
inconsistent
VOR in central disorders is…
low-sodium diet
Diet often advised for Meniere’s?
balance
The role of the ____ system is to provide accurate information about our position in space and about the direction and speed of our movement
falling
the balance system serves to prevent ____ by rapidly correcting for any changes that might occur in body position with respect to gravity
eye
The system functions to control ____ movement to maintain accurate vision during head movement
vary
The contributions of the visual, vestibular, and somatosensory systems ____ as a function of what we are doing at the moment
vestibular
The ____ portion of the inner ear consists of a fluid-filled membranous labyrinth within the bony labyrinth of the temporal bone
five sensory receptors
The membranous labyrinth contains ____ ____ ____:
Otolith organs
Utricle
Saccule
Semicircular canals
Superior (anterior)
Horizontal (lateral)
Posterior canals
hair cells
The vestibular system uses ____ ____, similar to the auditory system, each with many stereocilia and one taller kinocilium
opposite
When the head or body moves, fluid shifts in the ____ direction, stimulating vestibular hair cells and increasing activity in the vestibular branch of the VIII nerve
motion and gravity
Vestibular hair cells respond to both ____ & ____, helping the body detect changes in position & movement
increases; excitatory
Movement of stereocilia toward the kinocilium ____ electrical activity & creates an ____ neural response
decreases; inhibitory
Movement of stereocilia away from the kinocilium ____ electrical activity & creates an ____ neural response
angles
The semicircular canals are positioned at right ____ to each other, allowing them to detect angular and rotational head movements
ampulla
Each semicircular canal contains an _____ at its entrance, which houses sensory hair cells
cupula
These hair cells extend into a gelatinous structure called the ____
When the head moves, fluid inside the semicircular canals shifts, pushing against the cupula & bending the embedded cilia.
This bending of the cilia stimulates the hair cells, enabling the detection of rotational motion
horizontal; vertical
The utricle and saccule detect head tilt & linear acceleration, with the utricle responding mainly to ____ acceleration & the saccule to ____ acceleration
otoconia
In both structures, hair cells extend into a gelatinous membrane that contains calcium carbonate crystals called ____
more
The added weight of the otoconia makes the membrane ____ sensitive to gravity, allowing the hair cells to detect changes in head position & movement
vestibular
____ Nerve:
Vestibular nerve division → Formation of Scarpa’s ganglion → Central connections
superior; inferior
Vestibular nerve division
Nerve fibers from the otolith organs & semicircular canals exit through two branches: the ____ (from the superior semicircular canal (SCC), lateral SCC, and utricle) & the ____ vestibular nerve (from the posterior SCC & saccule)
scarpa’s
Formation of _____ ganglion
These nerve fibers converge at the lateral end of the internal auditory canal, forming ____ (vestibular) ganglion
ascending and descending
Central connections
After entering the brainstem, the vestibular nerve splits into _____ & _____ branches, which synapse in multiple vestibular nuclei & the cerebellum
gaze; vestibulo-ocular
The vestibular system helps stabilize ____ during head movement through a built-in connection between the vestibular & ocular motor systems
This connection produces a reflexive eye movement called the ____-____ reflex, which sends excitatory or inhibitory signals from the horizontal semicircular canal to the vestibular nuclei after head motion
compensatory
The vestibular nuclei then signal the eye muscles to create _____ eye movements
Horizontal VOR
Vertical VOR
horizontal VOR
Eyes move left when the head turns right
vertical VOR
Up/down eye movements maintain stable vision
eye
Understanding the VOR is essential because many vestibular tests measure ____ movements as an indicator of vestibular system function
medical
Balance problems can arise from non-vestibular causes, including ____ conditions such as high blood pressure, diabetes, neurological disorders, & certain medications
vertigo
a key sign of a vestibular disorder, involving an abnormal sensation of motion
mismatch
When the vestibular system is damaged, it sends inaccurate signals about head or body movement to the brain, creating a ____ between actual movement & perceived movement, resulting in an illusion of motion
vestibular
Disorders of the _____ System:
BPPV
Superior Canal Dehiscence (SCD)
Vestibulotoxicity
Vestibular Neuritis/Labyrinthitis
Ménière’s Disease
Vestibular Migraine
Central Balance Disorders
Benign Paroxysmal Positional Vertigo (BPPV)
A peripheral vestibular disorder caused by dislodged otoconia that migrate into a semicircular canal (most commonly posterior). |
Benign Paroxysmal Positional Vertigo (BPPV)
Causes:
Aging, head trauma, viral illness, idiopathic
Benign Paroxysmal Positional Vertigo (BPPV)
Symptoms:
Brief episodes of vertigo triggered by head position changes; nystagmus
Superior Canal Dehiscence (SCD)
A thinning or opening (dehiscence) in the bone overlying the superior semicircular canal |
Superior Canal Dehiscence (SCD)
Causes:
Congenital weakness, trauma, pressure changes, progressive bone thinning
Superior Canal Dehiscence (SCD)
Symptoms:
Sound/pressure-induced vertigo (Tullio phenomenon), autophony, conductive hearing loss, oscillopsia
Vestibulotoxicity
Damage to the vestibular hair cells or nerve due to ototoxic medications |
Vestibulotoxicity
Causes:
Aminoglycosides (gentamicin, tobramycin), chemotherapy drugs (cisplatin), high-dose loop diuretics
Vestibulotoxicity
Symptoms:
Oscillopsia, imbalance, difficulty walking in the dark, bilateral vestibular hypofunction
Vestibular Neuritis / Labyrinthitis
Inflammation of the vestibular nerve |
Vestibular Neuritis / Labyrinthitis
Causes:
Viral infections, post-viral inflammation