Infection and response triple content
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5 Terms
monoclonal antibody
made from a single clone of cells (so all are genetically identical)
what is an antibody? (3 key points)
made from white blood cells
has a shape that is complimentary to a specific antigen
causes pathogens to clump together so they can be easily found by phagocytes
how are monoclonal antibodies produced?
a mouse is vaccinated so it produces antibodies
spleen cells that from antibodies are collected from mouse
spleen cells are fused with tumour (myeloma cells) which reproduce quickly
hybridoma cells formed and grown in laboratory
antibodies are collected from hybridoma cells
how can monoclonal antibodies be used in cancer treatment?
when a cancer drug is attached to a monoclonal antibody, it only targets cancer cells
how can monoclonal antibodies be used in research?
when a fluorescent dye is attached to a specific antibody, it only binds to a specific antigen which can then be identified
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