Nucleophile/Base
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4 Terms
1
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What makes a good nucleophile?
1) negative charge
2) low EN
3) bigger atom
4) polar protic —> Nu increases down; polar aprotic Nu increases up
5) less bulky
2
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What makes a good leaving good?
1) weak base
2) conjugate of strong acid
3) weaker base than the nucleophile/base
3
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If you have a bad leaving good, what can you do?
convert it into their conjugate acid through addition of a strong acid (or Lewis acid)
4
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What reaction mechanism does polar aprotic solvents favor?
SN2
Note 
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