BTE1017: Commercial Biotechnology & Biopharma Lecture 8

Vocabulary flashcards focused on key terms and concepts from the BTE1017 Lecture on Therapeutics & Personalised Medicine.

Personalised Medicine

A medical model that tailors healthcare, with decisions and treatments tailored to individual patient characteristics.

Pharmacogenomics

The study of how genes affect a person's response to drugs, aimed at tailoring drug therapy to individuals.

Genomics

The study of the complete set of genes in an organism and their functions.

Proteomics

The large-scale study of proteins, particularly their functions and structures.

Metabolomics

The study of metabolites and metabolic processes within an organism.

Signal Transduction

The process by which a chemical or physical signal is transmitted through a cell as a series of molecular events.

Theranostics

An approach that links a diagnostic test with a therapeutic intervention tailored to an individual patient.

Targeted Therapy

A type of cancer treatment that uses drugs or other substances to identify and attack specific cancer cells.

Biomarker

A biological molecule found in blood, other body fluids, or tissues that can indicate a normal or abnormal process, or a condition or disease.

Epi-genetic

Referring to modifications that affect gene activity without changing the DNA sequence.

SNP (Single Nucleotide Polymorphism)

A variation in a single base pair in a DNA sequence.

UGT1A1 gene

A gene that provides instructions for making a specific enzyme involved in drug metabolism.

BCR-ABL Fusion Gene

A gene produced from a chromosome abnormality that often occurs in chronic myeloid leukemia.

HER2 Protein

A protein that can promote the growth of cancer cells, particularly in breast cancer.

AmpliChipCYP450

A genetic test for mutations in drug-metabolizing enzymes that was the first FDA approved pharmacogenetic test.

Pharmacogenetics

A branch of pharmacology concerned with the effect of genetic factors on drug response.

Gene-centered research

Research focused on individual genes and their role in diseases and drug responses.

Cost implications

The financial considerations associated with using specific therapies, treatments, or technologies.

Precision Medicine

An innovative approach to disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle.