Plasma
Fluid portion of the blood \n - has soluble proteins \n \n purpose: Concentration of plasma proteins helps \n control the osmotic balance in the blood \n (i.e Stops excess water from exiting the blood)
Albumins
maintain fluid levels by osmotically drawing water back into the capillaries
Fibrinogens
aid in blood clotting
immunoglobins
antibodies and carrier/transport proteins
Erythrocytes
Erythrocytes
AKA Red blood cells (RBCs) \n \n 4-6 million per mm3 of whole blood \n \n Function: to transport gas around the \n body
Biconcave disks
structure of Erythrocytes
increased surface area (for hemoglobin)
increases ability to exchange gas (Oxygen)
Hemoglobin
Red iron containing pigment
heme group
portion of molecule forms an \n unstable, reversible bond with oxygen. \n • Carries 20 ml oxygen per 100 ml of blood
Leukocytes
AKA white blood cells \n (General term for a variety of cells without hemoglobin) \n Important part of the immune system. \n - able to enter fluids surrounding tissues \n to fight infection, destroys pathogens
Neutrophils
most abundant WBC, phagocytic
Basophils
granules stain deep blue and release histamine
Eosinophils
granules stain red, phagocytize allergens
Lymphocytes
T and B cells, play roles in immunity
Monocytes
Largest WBC's, phagocytic \n - Differentiate into macrophages and dendritic cells
Granulocytes
have visible granules in cytoplasm
Arganulocytes
lack visible granules
Phagocytic
the process by which cells surround and digest certain particles
Platelets
(<1%) cell fragments
fragmentation of large cells called megakaryocytes
Tiny cells that play important role in blood clotting.
Hematocrit
Blood test that measures the percentage of \n your blood volume that is erythrocytes
Antigen
Antigens (proteins) on the surface of \n erythrocytes allow our body to recognize our own cells
Antibody
An antibody (Ab), also known as an immunoglobulin (Ig), is a large Y-shaped protein produced. \n \n Antigens that your body doesn't have, stimulate your body to form antibodies
Aglunation/ Agglutination
the cells to clump together
Rh factor
Rhesus Factor \n Named for the rhesus monkey \n Based on the ability to MAKE an antigen! \n \n positive (Rh+): can make the Rh antigen \n \n Rh negative (Rh-): cannot make the antigen
Universal donor
O negative \n Naked blood, has no antigens! Does not trigger an immune response from any blood type
Universal receiver
AB+ \n universal receiver, has no antibodies
Arteries
Carries blood to body
Veins
Carry blood back to the heart
Arterioles
Arteries branch into smaller vessels called Arterioles \n Middle layer of wall is mostly smooth muscle \n Important in control of blood pressure
Venules
small vessels that gather blood from the capillaries into the veins
Capillaries
Smallest blood vessels \n Connect arterioles to venules
Varicose veins
Caused when valves in veins stop functioning properly \n \n - Allows blood to flow backwards, and blood pools in veins
Arteriosclerosis
General term for when the wall of an artery becomes thicker and less elastic
Osmotic pressure
Generally causes water to move from tissues to blood; due to presence of plasma proteins and salts
Hydrostatic Pressure
- blood pressure \n Generally causes water to move from blood to tissues
artia
Singular: Atrium \n Thin walled \n Top portion of the heart
ventricle
thick muscular walls, bottom portion of the heart
myocardium
cardiac muscle
atrioventricular valves
Lie between the atrium and ventricle on each side
mitral valve
between the left atrium and left ventricle
bicuspid valve
between the right atrium and right ventricle
semilunar valves
Between the ventricle and great vessel on each side
aortic valve
between the left ventricle and aorta
pulmonary valve
between the right ventricle and the pulmonary artery
aorta
Largest artery in the body
inferior vena cava
A vein that is the largest vein in the human body and returns blood to the right atrium of the heart from bodily parts below the diaphragm.
superior vena cava
A vein that is the second largest vein in the human body and returns blood to the right atrium of the heart from the upper half of the body.
systole
contraction of heart muscle
diastole
relaxation of heart muscle
Sinoatrial node
A bundle of specialized nerves and muscles - \n located where the vena cava enter the right atrium \n \n sends a signal over to the two atria
atrioventricular node
Located the lower part of the right atrium close to the tricuspid valve \n - picks up electrical impulses
Purkinje fibres
two large nerve fibres run through the septum,
tachycardia
Fast heart beat heart rate exceeds 100 beats per min \n - can result from exercise or from the consumption of such drugs as caffeine or nicotine.
bradycardia
Slow heart beat Heart beat \n - lower than 60 bpm Can result from degeneration of the muscle (age), disease
electrocardiogram
EKG/ECG \n test that measures the electrical activity of the heart. \n -Traces how long the electrical wave takes to pass through your heart
p wave
first little hump - atria receives signal and contracts
qrs complex
Ventricles receive signal and contract \n -May just be an RS... this is still normal \n R wave is the first wave \n ABOVE the midline
t wave
Recovery of the heart
systolic number
the pressure when your heart contracts and pushes blood out \n - Highest pressure
diastolic number
the lowest pressure when the heart relaxes between beat
Sphygmomanometer
AKA Blood pressure cuff Measures blood pressure indirectly -Measures the pressure exerted by blood in the brachial artery HOW IT WORKS: *Placed on Brachial artery
Blood flowing through the brachial artery makes no noise
Pressure is slowly lowered until the blood is able to flow past, this is the systolic pressure (you'll hear a beat)
Pressure continues to be lowered until the noise disappears (diastolic pressure)
cardiac output
The volume of blood pumped from the heart each minute - \n Increased output will increase blood pressure. \n Raising your heart rate increases output!
arteriolar resistance
Diameter of the arterioles is regulated by muscles in their walls