Pathoanatomy (General Pathology - Sample MCQs)

1. Is it true that: Disease is a significant disturbance of the homeostasis due to changes in the environment or disturbance in the rebound responce of the individual.

a) yes

b) no

a) yes

2. Is it true that: Health is a state of imbalance of the organism with the external environment which doesn’t allow it to realize its biological potential

a) yes

b) no

b) no

3. Is it correct that etiology studies the causes of the diseases?

a) yes

b) no

a) yes

4. Is it correct that pathogenesis studies the mechanisms of healing from a disease?

a) yes

b) no

b) no

5. Is it true that morphogenesis studies the consequences of structural changes in the

course of a disease?

a) yes

b) no

a) yes

6. Is it true that sanogenesis studies the mechanisms of development of a disease?

a) yes

b) no

b) no

7. Is it true that tanatogenesis studies the changes which occur in the process of death?

a) yes

b) no

a) yes

8. Is it true that pathomorphosis studies the microscopic and gross changes in the course

of a disease?

a) yes

b) no

b) no

9. Is it true that cytology is a slow and very informative method?

a) yes

b) no

b) no

10. Is it true that biopsy is a slower method but gives maximum information and allows

more tests to be done like genetics?

a) yes

b) no

a) yes

11. Is it true that Van Gieson stain proves collagen fibres that stain in red.

a) yes

b) no

a) yes

12. Is it true that PAS reaction is used to prove glycogen which stains in yellow?

a) yes

b) no

b) no

13. Is it true that Sudan III is used to prove lipids and they stain in orange?

a) yes

b) no

a) yes

14. Is it true that Sudan IV is used to prove lipids and they stain in red?

a) yes

b) no

b) no

15. Is it true that Perls reaction is used to prove hemosiderin which stains in (Prussian)

blue?

a) yes

b) no

a) yes

16. Is it true that Toluidine Bleu stain used to prove glucosaminoglycans and the tissue

demonstrates metachromasia in pink-violet color?

a) yes

b) no

a) yes

17. Is it true that Congo red is used to prove hyaline which stains in "brick red" and shines

like "a green apple" on a polarized light?

a) yes

b) no

b) no

18. Do intracellular accumulations depend on the type and intensity of the injurious

stimuli?

a) yes

b) no

a) yes

19. Is it possible that a tattoo can lead to enlargement and inflammation of the local lymph

nodes?

a) yes

b) no

a) yes

20. Exogenous pigments are divided into organic and nonorganic.

a) yes

b) no

a) yes

21. Endogenous pigments are divided into hemoglobinogenous and nonhemoglobinogenous

a) yes

b) no

a) yes

22. Hemoglobinogenous pigments are divided into iron-containing and non-iron

containing.

a) yes

b) no

a) yes

23. Bilirubin is iron-containing pigment.

a) yes

b) no

b) no

24. Hemosiderin is non-iron-containing pigment.

a) yes

b) no

b) no

25. Melanin, lipofuscin and adrenochromes are endogenous hemoglobinogenous

pigments.

a) yes

b) no

b) no

26. Hepatocellular jaundice can be seen in malaria and some types of anemia.

a) yes

b) no

b) no

27. Obstructive jaundice can be seen in cancer of the head of pancreas and in

choledocholithiasis

a) yes

b) no

a) yes

28. Haemolyc jaundice is seen in acute hepatitis and in mushroom poisoning.

a) yes

b) no

b) no

29. Is sclerosis the end stage of fibrosis?

a) yes

b) no

a) yes

30. 105. Is it true that cirrhosis doesn't cause deformation of the affected organ?

a) yes

b) no

b) no

31. Is it true that fibrinoid necrosis damages the fibrillary structures of the extracellular

matrix but also the cells in the focus?

a) yes

b) no

a) yes

32. Is it true that fibrosis is only a physiological process and cannot lead to organ

deformation and dysfunction?

a) yes

b) no

b) no

33. Is it true that grossly, uric acid crystals are white painful nodules on the skin, usually

on the extensor surfaces on the extremities

a) yes

b) no

a) yes

34. Is it true that the capacity of cell proliferation is the most important factor for the

development of hypertrophy or hyperplasia?

a) yes

b) no

a) yes

35. Is it true that dysplasia means that cancer has already developed?

a) yes

b) no

b) no

36. Is it true that dysplasia can be found together with cancer?

a) yes

b) no

a) yes

37. Is thrombus formation possible in the heart cavities?

a) yes

b) no

a) yes

38. Are thrombosis and coagulation in normal homeostasis one and the same process?

a) yes

b) no

b) no

39. Is it true that inflammatory and immune reactions are completely independent

reactions of the organism against pathological agents?

a) yes

b) no

b) no

40. Is it true that hypersensitivity of immediate type is related to chronic inflammatory

reactions?

a) yes

b) no

b) no

41. Is it true, that hypersensitivity of delayed type IV is related to chronic inflammatory

reactions?

a) yes

b) no

a) yes

42. Are necrosis and hemorrhages typical findings in adenomas?

a) yes

b) no

b) no

43. Is peritonitis possible complication of colon cancer?

a) no

b) yes

b) yes

44. Is breast fibroadenoma a precancerous lesion?

a) yes

b) no

b) no

45. Is fibroadenoma a malignant tumor?

a) yes

b) no

b) no

46. Do benign tumors arising from the smooth muscles have a capsule?

a) no

b) yes

a) no

47. Do hemangiomas have a capsules?

a) yes

b) no

b) no

48. Are hemorrhages and necrosis in the smooth muscle tumors of uterus a typical sign for

malignancy?

a) yes

b) no

b) no

49. Is it true that lymphomas are benign tumors?

a) yes

b) no

b) no

50. Are there benign tumors arising from the hemopoetic tissues?

a) yes

b) no

b) no

51. Can hydropic degeneration lead to necrosis of the cells?

a) yes

b) no

a) yes

52. Does PAS- reaction identifies glycogen in the cells?

a) yes

b) no

a) yes

53. Is hypoxia an important factor for the development of fatty degeneration?

a) yes

b) no

a) yes

54. Can gall bladder contain uric acid crystals?

a) yes

b) no

b) no

55. Is a hypoxia an important factor for development of the fatty degeneration?

a) yes

b) no

a) yes

56. Is uric acid infarction related to a circulatory disorder?

a) yes

b) no

b) no

57. Is a deposition of the glycogen in the epithelium of the renal tubules a feature of

diabetes?

a) yes

b) no

a) yes

58. Does plasma leakage play an important role in the development of hyalinosis?

a) yes

b) no

a) yes

59. Are lysosomal enzymes important in the inflammatory processes?

a) yes

b) no

a) yes

60. Is endothelial injury important for thrombosis?

a) yes

b) no

a) yes

61. Is formalin a suitable fixative for demonstration of neutral lipids?

a) yes

b) no

a) yes

62. Perls' reaction is used for demonstrating hemosiderin:

a) yes

b) no

a) yes

63. Could hemolytic jaundice be seen in the newborn?

a) yes

b) no

a) yes

64. Is the development of amyloidosis possible in systemic diseases of the connective

tissue?

a) yes

b) no

a) yes

65. Can thrombosis lead to the embolism?

a) yes

b) no

a) yes

66. Is coagulative necrosis seen in cerebral infarction?

a) yes

b) no

b) no

67. Does apoptosis affect a large group of cells?

a) yes

b) no

b) no

68. Does necrosis affect the cells and extracellular matrix?

a) yes

b) no

a) yes

69. Is hemosiderin an iron-containing pigment?

a) yes

b) no

a) yes

70. Do tumors reverse spontaneously and return to normal structures?

a) yes

b) no

b) no

71. Could serous inflammation be seen in myocardium?

a) yes

b) no

b) no

72. Is there a central necrosis in syphilitic granuloma?

a) yes

b) no

a) yes

73. Are benign tumors encapsulated?

a) yes

b) no

a) yes

74. Is serous inflammation a type of exudative inflammation?

a) yes

b) no

a) yes

75. Is a glomus angioma a vascular tumor?

a) yes

b) no

a) yes

76. Is metahromasia stained with toluidine blue characteristic for mucoid swelling?

a) yes

b) no

a) yes

77. Is there a serous inflammation in the myocardium?

a) yes

b) no

b) no

78. Can benign tumors lack capsule:

a) yes

b) no

a) yes

79. Is metachromasia characteristic for the mucoid degeneration?

a) yes

b) no

a) yes

80. Blood vessels are present in the tubercle granuloma?

a) yes

b) no

b) no

81. Glomus-tumor belongs to endothelial tumors.

a) yes

b) no

a) yes

82. Benign tumors may not have a capsule:

a) yes

b) no

a) yes

83. Are the plasma cells characteristic for tubercle granuloma?

a) yes

b) no

b) no

84. Is there a coagulative necrosis in brain infarction?

a) yes

b) no

b) no

85. Can thrombus in v. portae cause arterial emboli in art. pulmonalis ?

a) yes

b) no

b) no

86. Is it true that gross changes of the organs are important for the diagnosis?

a) yes

b) no

a) yes

87. Is brown induration of lungs a reversible change if the mitral stenosis, which cause it,

is corrected by a mitral valve prosthesis?

a) yes

b) no

b) no

88. Is it true that amyloid is an abnormal protein that accumulates in the extracellular

space and lead to hypertrophy of the parenchymal cells and increased function of the

organ?

a) yes

b) no

b) no

89. Precancerous lesions may have a reverse development (back to normal tissue):

a) yes

b) no

a) yes

90. Is there a characteristic macroscopic appearance in organs with hyaline degeneration?

a) yes

b) no

a) yes

91. Is it possible to find lymphocytes in the focus of acute inflammation?

a) no, lymphocytes are chronic inflammatory cells only

b) yes, they can be seen in the focus of acute inflammation when the etiologic

agents are viruses

b) yes, they can be seen in the focus of acute inflammation when the etiologic

agents are viruses

92. Is it possible to find neutrophiles in the focus of chronic inflammation?

a) yes, in case of chronic abscess

b) no, neutrophiles are seen in case of acute inflammation only

a) yes, in case of chronic abscess

93. Lipoma is a benign tumor from:

a) epithelial

b) mesenchymal origin

b) mesenchymal origin

94. Specify the characteristic localization of intracellular hyaline degeneration:

a) liver cells

b) vascular endothelium

a) liver cells

95. When is deathpossibly reversible?

a) clinical features of death

b) biological death

a) clinical features of death

96. Indicate which cells are found in the granuloma "foreign body" type

a) giant cells Langhans type

b) macrophages

b) macrophages

97. What may be the ultimate outcome of chronic venous congestion in the liver:

a) cardiac cirrhosis

b) brown induration

a) cardiac cirrhosis

98. What kind of jaundice develops in cancer of the papilla Vateri?

a) mechanic

b) hemolytic

a) mechanic

99. Basal cell cancer is localized most frequently:

a) forearm skin

b) facial skin

b) facial skin

100. Lymphangiomas locate most often:

a) on the face

b) on lips, tongue

b) on lips, tongue