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multiplication rule
apply when two events occur simultaneously
addition rule
apply when two events are mutually exclusive
shortest path
apply when there are many “paths” to giving a probability
conditional probability
occurs when we must apply a specific condition to a probability
In a pile of cards with six equally possible colors (red, blue, green, black, yellow, orange), what is the probability of drawing a red card?
1/6 chance
P(Red and Blue)
1/6 ×1/6 = 1/36
multiplication rule
P(Red or Blue) = P(Red) + P(Blue)
1/6 + 1/6 = 2/6 = 1/3
P(Not Red) = 1 - P(Red)
1 - 1/6 = 6/6 - 1/6 = 5/6
P(Red, then Blue, then Orange)
1/6 × 1/6 × 1/6 = 1/216
cystic fibrosis
caused by an autosomal recessive allele, leading to thick mucus buildup that affects multiple organ systems
genotype ratio
For two heterozygous pairs: 1:2:1 for both A and B.
Possible combinations of alleles (AA, Aa, aa with BB, Bb, bb) give 9 unique genotypes.
phenotype ratio
For a dihybrid cross with complete dominance: typical phenotype ratio: 9:3:3:1
method 1 - dihybrid punnett square
Create a 4x4 grid to represent all combinations for AaBb x AaBb
Resulting genotype ratio: 9 unique combinations
method 2 - multiplication rule
For independent traits, multiply individual trait probabilities: P(Aa) = 1/2, P(Bb) = 1/2
To get the probability of a specific combination, multiply these probabilities together.
method 3 - forked-line method
Use a forked-line diagram to separate the two traits (A and B).
Follow the possible combinations for each trait and multiply the probabilities for independent inheritance.
forked-line method
forked-line diagram method simplifies complex genetic crosses by visualizing the probabilities of each trait separately