Peptidases and Proteases

what is the func. of Carboxypeptidase A

C terminal end cleavage of P, R, K

what is the function of Aminopeptidase?

N terminal cleavage unless residue is next to proline

what is the function of carboxypeptidase B?

C terminal cleavage of R and K cuz fk Proline

What is the func. of Trypsin?

Cuts off C terminal of R and K (Basic Residues)

What is the function of Chymotrypsin?

Cuts C side of F, W, Y (Has Aromatic Rings)

Function of Papain?

Cuts C side bonds of Aromatic Groups and Hydrophobic residues

What are the hydrophobic residues (Mnemonics for Hydrophobic/Non-Polar = MCAT Grades Are Like Fights, I Will Prove Victorious )

• Methionine

• Glycine

• Arginine

• Phenylalanine

• Isoleucine

• Twyptophan

• Proline

• Valine

Function of Cyanogen Bromide?

C side cleavage of internal Methionine

function of clostripain?

cleaves c terminal side of Arginine

func of thermolycin?

Cuts C side of Serine