CNS Drugs: Antipsychotics, Antidepressants, Mood Stabilizers
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Last updated 3:45 PM on 9/5/25
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30 Terms
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chlorpromazine
typical antipsychotic, low potency, sedating
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haloperidol, decanoate classes
typical antipsychotic, D2, alpha, and serotonin agonist
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haloperidol, decanoate kinetics
variable onset, CYP450, watch WBC count
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quetiapine, aripiprazole classes
atypical antipsychotic, dopamine stabilizer
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quetiapine, aripiprazole side effects
weight gain, menstrual, libido decrease, osteoporosis, seizures, agranulocytosis, type 2 diabetes, NO EPS
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olanzapine, omeprazole classes
atypical antipsychotic
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olanzapine, omeprazole dynamics
control positive + negative symptoms
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olanzapine, omeprazole side effects
fewer EPS, headache, fever, GI, anorexia, NMS, tardive dyskinesia, weight gain, diabetes, hypotension
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phenelzine, selegiline classes
MAOI antidepressant
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phenelzine, selegiline interactions
tyramine, amphetamines, allergy, decongestants, antidepressants, antihistamines, anti-HTN, levodopa, meperidine. so like everything
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nortriptyline classes
TCA antidepressant
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nortriptyline kinetics
absorbed hepatic 1st pass, protein bound P450
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nortriptyline side effect
altered blood glucose
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sertraline classes
SSRI antidepressant
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sertraline kinetics
protein bound P450
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sertraline caution
liver disease
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fluoxetine classes
SSRI antidepressant
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citalopram classes
SSRI antidepressant
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escitalopram classes
SSRI antidepressant
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paroxetine
SSRI antidepressant, anti-ACh
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duloxetine, venlafaxine classes
SNRI antidepressant
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bupropion
NDRI, lower seizure threshold, additive w/SSRI
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trazodone
A1+A2 agonist antidepressant, sleep aid, hypotensive, priapism
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lithium class
mood stabilizer
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lithium dynamics
NE, ACh, GABA, Dopa antagonist, transports Na across cell membrane
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lithium kinetics
well absorbed PO, not metabolized by the body, 80% reabsorbed by kidney
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lithium considerations
toxic if low Na, non-therapeutic if high Na
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lithium 0.6-1.2 mEq/L side effects
metallic taste, nausea, polyuria, polydipsia, diarrhea, weakness, edema, weight gain, tremors
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lithium 1.2-2.5 mEq/L side effects
severe N + V, dizzy, slurred speech, blurred vision, twitching, tremors
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lithium toxicity effects
nystagmus, oliguria, low BP, confusion, choreiform movements, convulsions, coma
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