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Theory
In science, a well-substantiated, overarching explanation of some aspect of the natural world. It is based on large amount of data and is presented as a cohesive argument that explains this data in a mechanistic manner
Law
In science, statement of an order or a relation of phenomena that semm invariable under a given set of conditions
Fact
An observation that has been repeatedly confirmed. For example, there are 23 pairs of chromosomes in human cells.
Hypothesis
A testable statement about the natural world that can be used to build more complete inferences and explanations. It explains why something occurs.
Uniformitarianism
School of geological thought assuming that geological phenomena were the product of a consistent set of natural forces operating on the planet over very long periods of time
unchanging
the dominant view of species prior to Darwin's work was that species were
Induction
In the logic of science, the process of reasoning from a part to the whole, or from particular instances to greater generalities
Pangenesis
Darwin's hypothesis of heredity was termed
4.0 billion years
Approximately how old is the earth?
minister
Darwin graduated from college as a....
environment
Darwin felt that the ultimate source of variation in organisms was caused by
Principle of segregation of unit characters
When a diploid organism that is heterozygous at a particular gene locus undergoes meiosis 50% of its gametes will carry the other allele.
fitness
The following is a definition for which of the terms listed below? "The ability of an individual or a population to leave viable progeny in relation to the ability of other individual or populations
transcription
stage of gene expression in which an RNA copy is synthesized from a DNA template
gene
a set of nucleotide sequences that encode the amino acid sequence of an enzyme or other type of protein
True
Only mutation in germ cells are heritable
spandrel
A roughly triangular space; usually found in pairs, between the tops of an arch and rectangular frame, between the tops of two adjacent arches, or one of the four spaces between a circle within a square. They are frequently filled with decorative elements
adaptationist program
the process of breaking an organism into unitary traits and proposing an adaptive story
Dr. Pangloss
Who said, "Everything is made for the best purpose? Our noses were made to cry spectacles, so we have spectacles. Legs were clearly intended for breeches, and we wear them
Anagenesis and Cladogenesis
Evolutionary history is composed of a series of speciation events. This history of speciation involves two fundamental elements. What are they?
Karl Popper
Wrote the Logic of Scientific Discovery and provided one of the most influential and controversial view on the 'problem of induction'?
No
Are all questions relevant to scientific inquiry?
Ultraviolet Radiation
Based on our discussions in class, pyrimidine dimers are formed by which of the following mutagens
Frame shifts
Slipped mispairing in the middle of a codon is thought to give rise to which class of mutations.
Wallace
Who is credited, along with Darwin, as the co-discoverer of 'natural selection'?
Gould and Lewontin
Who wrote the paper we read in class that was a critique of the 'adaptionist program'?
Translocation
The process in which a segment of one chromosome becomes a part of another chromosome
Species
What is the highest level of biological organization at which the evolutionary process occurs?
Pine forests in Nova Scotia
Which of the following places did Darwin not visit on his five-year voyage on H.M.S. Beagle?
No
Did most people (as in the majority of humans) during Darwin's time believe in evolution?
Allele
One or more alternative states of a gene
27.9%
Upon sampling a population of darters from the Meramec River, you find the following gene frequencies. What is the frequency of the "a" allele?
AA: 34 Aa:17 aa:8
10.24%
Consider question 2, 3, and 4 in light of this data Upon sampling a population of darters from the Meramec River for a single locus with two alleles, you find the following allele frequencies. A=32% a=68%
If the population were in Hardy-Weinberg equilibrium, what would you expect the frequency of the "AA" genotype to be.
43.52%
A=32% a=68%
If the population were in Hardy Weinberg equilibrium, what would you expect the frequency of the "Aa"
genotype to be
38.37%
A=32% a=68%
If the population were in Hardy Weinberg equilibrium and you had initially sampled a total of 83 individuals, how many individuals would you expect to have the "aa" frequency
29.20
Upon sampling a population of darters from the Osage River for a single locus with two alleles, you find the following genotype array. AA=37 individuals Aa=23 ind. aa=40 ind.
Given your analysis of these data in light of hardy-weinberg expectations, you expect the following genotype array. AA: 23.5 individuals Aa: 50 ind. aa: 26.5 ind. What is the approximate value of chi square for these data?
No
Is the population of darters sampled in question 5 in Hardy-Weinberg equilibrium?
Not change
If all the assumptions of the hardy Weinberg model are met, after one generation of random mating genotype frequencies will...
There is random mating
When a given individual has an equal probability of mating with any individual of the opposite sex within the population, we can safely say that...
The condition of having more than a single allele at a gene locus
Choose the best response. In a population of diploid organisms, polymorphism is best defined as...
A. Infinitely Large population
B. Random Mating
C. Low rate of migration
D. Low level of selection
E. Two of the Above (correct answer)
Which of the following is not an assumption of the Hardy-Weinberg model?
Most individuals are heterozygous for at least a few bad alleles
What is the primary reason that "Everyone knows that close inbreeding is bad."-Unknown
Larger
As a population departs from an infinite size (gets smaller), the contributions of genetic drift to the evolutionary process become:
No
Do proponents/advocates of the Neutral Theory maintain that natural selection does not occur?
Directional Selection
The two graphs at the right depict a population at Time 0 and the same population at Time 100 after 100 generations of a particular type of selection. Which type of selection is represented by the changes in the two graphs
Stabilizing selection
The two graphs at the right depict a population at Time 0 and the same population at Time 100 after 100 generations of a particular type of selection. Which type of selection is represented by the changes in the two graphs
Intermittent Drift (bottle neck)
Population bottlenecks (as in the cheetah, which is hypothesized to have shrunk to a very small population and then re-expanded) are most closely associated with which type of drift?
Infinitely large population, random mating
What are two of the most unrealistic assumptions of the Hardy-Weinberg model?
High mutation rate
Which of the following can be considered a destabilizing force?
False
Mutations occuring in somatic cells are thought to have a strong impact on the evolutionary process
True
Natural selection is thought to provide the overall "directional force" in the evolutionary process.
False
A silent substitution is an amino acid substitutiohn at the third codon position
Percent Heterozygosity
A measurement of the number of individuals in a population that possess more than one allele at a single locus
Dicot Angiosperms, Monocot angiosperms, gymnosperms
In terms of plants which is the correct order of polymorphism from lowest to highest?
False
If an organism is a heterozygote at a protein coding locus, each form of the protein (each allele) has been shaped by natural selection to give that organism an advantage in nature
True
Kimura's summation of the Neutral theory of Molecular Evolution maintains that at the molecular level, most evolutionary change and most of the variability within a species are not caused by selection, but by random drift of mutant genes that are selectively equivalent
False
The evidence that evolutionary rates are highest in non-transcribed DNA, in relatively functionless polypeptides, and for third codon position of coding regions are data that are considered to be inconsistent with the neutral theory of molecular evolution
It generally fails to detect changes at the third codon position
Why is protein electrophoresis considered to underestimate the true level of genetic variability within a population
Homozygosity
Genetic drift tends to drive populations toward
True
The paper we discussed in class by Allen Place and Dennis Powers (PNAS, 1979) on protein electrophoretic variation in the Mummichog (Fundulus heteroclitus) demonstrated that the allele common to cooler, northern waters coded for a protein with a higher rate of enzymatic catalysis at a cooler temperature. The allele common in southern waters coded for a protein with a higher rate of enzymatic catalysis at a warmer temperature.
False
The paper we discussed in class by Allen Place and Dennis Powers (PNAS, 1979) on protein electrophoretic variation in the Mummichog proved that if a protein coding locus is polymorphic within a species, each alternative form of the protein exists due to natural selection and is therefore an adaptation under the normal environmental conditions in which the organism lives
Fst=1
If two populations are fixed for different alleles at a single locus
Sea urchin
Based on the notes and our discussions in class, which type of organism has a higher level of polymorphism?
There are numerous studies that have sought to demonstrate the role of natural selection and the adaptive significance of many traits but a large portion were flawed by one or more common errors
Based on the notes and our discussions in class, which of the following statements would you judge to be most correct.
By measuring reduction in heterozygosity
How do we make the effects of inbreeding quatitative? (What are we measuring?)
F=0
When there is no inbreeding, which of the following is true at a polymorphic locus?
a. F=0
b. F=1 *
c. the population contains only homozygotes *
d. two of the following (correct answer)
When there is complete inbreeding, which of the following is true at a polymorphic locus
Intermittent Drift
A large population may occasionally shrink to a small size. At this point in time tremendous sampling error may be introduced. What do we call this?
The census size of the population
What does the symbol N represent in the equations we have been considering recently?
Selection
Which of the following evolutionary forces is thought to provide the overall "directional force in the evolutionary process"?
False
The evidence that evolutionary rates are highest in non-transcribed DNA, in relatively functionless polypeptides, and for third codon positions of coding regions are data that are considered to be inconsistent with the neutral theory of molecular evolution
It generally fails to detect changes at the third codon position
Why is protein electrophoresis considered to underestimate the true level of genetic variability within a population?
True
A cornerstone of the theory of evolution by gradual change is that the rate of evolution is absolutely limited by the amount of genetic variation in the evolving population
Mutation and extinction
The neutral theory of molecular evolution asserts that most intraspecific variability at the molecular level is maintained by a balance of which two factors?
when all mutations are neutral
According to Kimura when are the highest rates of evolution achieved?
Selection
Which of the following evolutionary forces is most powerful when 4N_es>>>>>>>>>>1?
A theoretical genotype
In the adaptive landscape, what do each of the infinite numbers of points on the theoretical terrain represent?
large population
In which type of population is a mutation with a slightly advantageous effect most likely to increase.
small population
In which type of population is a deleterious allele most likely to increase?
drift followed by selection
Which combination of evolutionary forces is most likely to drag a population off of one adaptive peak and onto another higher adaptive peak?
Fitness
In the adaptive landscape, what does the relative height of the peaks represent?
A large number of local races spread over a large portion of the adaptive landscape with low levels of gene flow connecting them
Which of the following conditions, according to Sewell Wright, is most likely to result in increased adaptation of a species to its environment?
Individual fitness
A type of fitness also referred to as viability
Relative fitness
The type of fitness typically referred to by evolutionary geneticists?
Absolute fitness
The type of fitness that is usually assigned to a genotype
In a one locus, two allele system, where one allele (A_2) is less fit than another allele (A_1), s=1-w2
How is the selection coefficient related to fitness?
Secondary theorem of natural selection
If a trait strongly covaries with relative fitness, it will change a lot from one generation to the next. If it does not strongly covary with relative fitness, it will not change a lot. Which of the following two terms does this statement define?
Fundamental Theorem of natural selection
The mean relative fitness of a population either increases or does not change under natural selection. Which of the following two terms does this statment define?
False
The neutral theory of molecular evolution denies the existence of natural selection and maintains that all evolutionary change is the result of genetic drift
True
Most population geneticists support the idea that the shift of co-adapted gene complexes from one adaptive peak to another is faciliatated by large population size
Fisher
Who developed the fundamental theorem of natural selection?
A. The vast majority of substitutions that occur at the molecular level are caused by random fixation of neutral mutations
B. Most intraspecific variability at the molecular level is selectively neutral
C. While advantageous mutations may occur, they are so rare that they can be ignored in quantitative considerations
D. All of the above (correct answer)
The neutral theory of molecular evolution holds which of the following statements to be true?
Founder effect
When a few individuals or only one reproductively competent individual start a new population, and this population differs in allele frequency from the parent population, we refer to this as which of the following?
Sewall Wright
Who was Motoo Kimura's idol when he was growing up?
Macroevolution
The observation that big evolutionary changes usually result from exploitation of a new ecological niche is referred to by Kimura as "liberation from selective constraint." Kimura goes on to state that this is a major cause of which of the following processes in evolution?
No
According to Fischer, can selection as an isolated evolutionary process act to reduce fitness?
Serial Homology
At position 1138 of the cytochrome b gene, most fish possess a C nucleotide residue, while humans possess a G residue. What type of homology do these two character states exhibit?
Synapomorphy
At position 1139 of the cytochrome b gene, rainbow darters and orangethroat darters (which are sister species) both possess a C nucleotide residue, while all other species of darters possess a T. What type of homology does the C nucleotide residue represent for Rainbow and Orangethroat darters?
Paraphyletic Group
A group that contains an ancestor and some but not all descendent taxa is best known as which of the following?
The genealogical relationships among populations and species may be recovered (discovered) by grouping the organisms based on overall similarity of appearance
Which of the following was not one of Willi Hennig's five basic ideas that began a major revolution in phylogenetics?