Biology Paper 1- 4.3.2 Monoclonal antibodies. (HT)

Scientist can use lab mouse to produce monoclonal antibodies to treat certain cancer.

Describe how monoclonal antibodies can be produced by using lab mouse. [5 marks]

• Inject antigen into the lab mouse to produce lymphocytes.

• Fuse lymphocytes with tumour cells to produce hybridoma cells.

• Select a single hybridoma cell that produce desired antibodies.

• Let hybridoma cell divided by mitosis to create clones.

• Collect the monoclonal antibodies from all hybridoma cells.

State 3 uses of monoclonal antibodies. [3 marks]

• pregnancy test.

• detect pathogens.

• treat certain disease.

State 1 disadvantage of using monoclonal antibodies. [1 mark]

Harmful side effect.

This topic is finished.