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Vaccine
antigens (proteins, etc.) introduced into body to
elicit a specific immune response for prophylaxis, post-
exposure, or disease treatment (e.g., cancer, drug addiction)
antigen-presenting cells (APC)
presenting a pathogen’s
antigens to Helper T cells (Th) that, in turn, activate other
immune cells (T and B cells)
Plasma B cells
produce antibodies to neutralize
pathogens (preventing them from associating with cells)
and label them for destruction
Killer T cells
rid body of labeled pathogens
Memory T and B cells
remember how to fight the
specific pathogen during subsequent infections
Mutations and/or recombination ➟
mmune evasion
(↑ opportunity in unvaccinated hosts)