Experiment 2 – Reductive Amination

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Flashcards about Reductive Amination

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8 Terms

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Amines

An important class of compounds found in pharmaceuticals, petrochemicals and materials.

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Condensation Reactions

Reactions between amines and aldehydes and ketones; the product imines are also known as Schiff bases.

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Reductive Amination

A reaction used to generate amines with an additional substituent. Aldehydes are more reactive than ketones in the condensation reaction.

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Aldehydes

More reactive than ketones in the condensation reaction.

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Schiff Base

The product of condensation reactions between amines and aldehydes/ketones.

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TLC (Thin Layer Chromatography)

Used to monitor the reaction in the experiment.

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UV/Vis and phosphomolybdic acid stain

Used to visualize the TLC plate.

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Biomolecules with Nitrogen

A major class of biomolecules that are prepared via reductive amination.