Amino Acid Properties: Polarity, pKa, and Charge at pH 7

Aspartate (Asp, D)

Acidic polar; pKa 3.9; Charge -1 at pH 7; Deprotonated

Glutamate (Glu, E)

Acidic polar; pKa 4.2; Charge -1 at pH 7; Deprotonated

Histidine (His, H)

Basic polar; pKa 6.0; Charge ~0 at pH 7; Mostly deprotonated

Lysine (Lys, K)

Basic polar; pKa 10.5; Charge +1 at pH 7; Protonated

Arginine (Arg, R)

Basic polar; pKa 12.5; Charge +1 at pH 7; Protonated

Cysteine (Cys, C)

Polar uncharged; pKa 8.3; Charge 0 at pH 7; Protonated

Tyrosine (Tyr, Y)

Polar uncharged; pKa 10.1; Charge 0 at pH 7; Protonated

Alanine (Ala, A)

Nonpolar; Charge 0

Valine (Val, V)

Nonpolar; Charge 0

Leucine (Leu, L)

Nonpolar; Charge 0

Isoleucine (Ile, I)

Nonpolar; Charge 0

Methionine (Met, M)

Nonpolar; Charge 0

Phenylalanine (Phe, F)

Nonpolar; Charge 0

Tryptophan (Trp, W)

Nonpolar; Charge 0

Proline (Pro, P)

Nonpolar; Charge 0

Glycine (Gly, G)

Nonpolar; Charge 0

Serine (Ser, S)

Polar uncharged; Charge 0

Threonine (Thr, T)

Polar uncharged; Charge 0

Asparagine (Asn, N)

Polar uncharged; Charge 0

Glutamine (Gln, Q)

Polar uncharged; Charge 0