Biochem - Glycolysis

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10 Terms

1
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Step 1: phosphorylation

glucose to glucose-6-phosphate

hexokinase

1 ATP to 1 ADP

2
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Step 2: isomerization

glucose-6-phosphate to fructose-6-phosphate

glucose-6-phosphate isomerase

3
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Step 3: phosphorylation

fructose-6-phosphate to fructose-1,6-bisphosphate

phosphofructokinase

1 ATP to 1 ADP

4
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Step 4: cleavage

fructose-1,6-bisphosphate to glyceraldehyde-3-phosphate and dihydroxyacetone phosphate

aldolase

5
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Step 5: isomerization

dihydroxyacetone phosphate to glyceraldehyde-3-phosphate

triose phosphate isomerase

6
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Step 6: oxidation/phosphorylation

(2) glyceraldehyde-3-phosphate to 2 (1,3-bisphosphoglycerate)

glyceraldehyde-3-phosphate dehydrogenase

2 NAD+ and 2 Pi to 2 NADH

7
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Step 7: substrate-level phosphorylation

(2) 1,3-bisphosphoglycerate to (2) 3-phosphoglycerate

phosphoglycerate kinase

2 ADP to 2 ATP

8
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Step 8: isomerization

(2) 3-phosphoglycerate to (2) 2-phosphoglycerate

phosphoglycerate mutase

9
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Step 9: dehydration

(2) 2-phosphoglycerate to (2) phosphoenolpyruvate

enolase

removal of H2O

10
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Step 10: substrate-level phosphorylation

(2) phosphoenolpyruvate to (2) pyruvate

pyruvate kinase

2 ADP to 2 ATP