BICD 110 Lecture 6 Golgi
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Last updated 7:05 AM on 4/24/25
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4 Terms
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Cisternal Maturation Model
The Golgi cisternae mature from cis to trans, enzymes are transferred between cisterne and the cargo does not move relative to the cisterna it’s in
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Vesicular Transport Model
The cisternae are static, and the enzymes stay in each cisterna. The cargo moves through cisternae through tubules and vesicles.
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Function of cis-Golgi
Remodeling of N-glycans
1) Removal of 3 Mannose by Mannosidase 1 and 2
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Function of medial Golgi
One GlcNAc added to N-glycan (transferred from UDP-GlcNAc), two more mannose resides removed
Note 
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