Antidepressants brands/dosages

Citalopram (generic)

Celexa (brand)

Citalopram dose

20-40mg/d; max 40mg/d (20mg/d in elderly >60yrs)

Escitalopram (generic)

Lexapro (brand)

Escitalopram dose

10mg/d; max 20mg/d (10mg/d in elderly)

Fluoxetine (generic)

Prozac (brand)

Fluoxetine dose

10-60mg/d

Max 80mg/d or 90mg/wk in DR

Switching from fluoxetine 20 mg immediate relase to 90mg/wk DR

Start 7 days after last dose

Fluoxetine + olanzapine (generic)

Symbyax (brand)

Symbyax dose

6mg/25mg qHS

Paroxetine (generic)

Paxil, Paxil CR (brand)

Paroxetine dose

IR: 10-60mg/d

CR: 12.5-62.5mg/d

(10 ir = 12.5 cr)

Paroxeine indicated for moderate-severe vasomotor symptoms in menopause

Brisdelle

Bridelle dose

7.5mg qHs

Sertraline (generic)

zoloft (brand)

sertraline dose

50-200mg/d

Fluvoxamine IR/ER dose

50-300mg/d (doses over 100mg/d should be BID)

Vilazodone (generic)

viibryd (brand)

vilazodone dose

10 mg/d x 7d then 20mg/d; max 40mg/d

vilazodone counseling

take wtih food

vortioxetine (generic)

trinellix (brand)

vortioxetine dose

5-20mg/d

vortioxetine counseling

take with or without food; may have to decrease dose 50% if using with strong CYP2D6 inhibitors

venlafaxine (generic)

effexor XR (brand)

venlafaxine dose

37.5-375mg/d

Max 375mg/d (IR) 225mg/d (ER)

Duloxetine (generic)

cymbalta (brand)

duloxetine dose

40-60mg/d (or 20-30BID)

Max 120mg/d; doses >60mg/d may not be effective

desvenlafaxine (generic)

pristiq (brand)

desvenlafaxine dose

50mg/d (no benefit above this, but can go up to 400mg/d)

levomilnacipran (Generic)

fetzima (brand)

levomilnacipran dose

20mg/d x 2d f/b 40mg/d. Can titrate up 40mg/d every 2 days

Max 120mg/d

Levomilnacipran counseling

do not open, chew or crush capsules; do not take wtih alcohol

Amitryptyline dose

100-300mg/d qHS or div doses

Doxepin (insomnia-generic)

Silenor (brand)

Doxepin (pruritus-cream)

Zonalon

Doxepin dose

100-300mg/d

Nortriptyline (generic)

Pamelor (brand)

Nortriptyline dose

25 mg TID-QID

Buproprion dosing

150-450mg/d

IR given TID

SR given BID (200mg/dose max)

XL given daily

MAX 450mg/d due to seizure risk

Buproprion + dextromethorpan

Auvelity

Auvelity dose

dextromethorphan 45mg/bupropion 105mg BID at least 8 hrs apart

Isocarboxazid (generic)

Marplan (brand)

Isocarboxazid dose

20mg/d in div dose (max 60mg/d)

Phenelzine (generic)

Nardil (brand)

Phenelzine dose

15mg TID (max 60-90mg/d)

Tranylcylopromine (generic)

Parnate (brand)

Tranylcypromine dose

30mg/d in div doses; max 60 mg/d

Selegiline trandermal patch

Emsam

Emsam dose

6mg patch/d; increase in increments of 3mg to max of 12mg/d

Mirtazapine (generic)

Remeron (brand)

Remeron dose

15-45mg qHS

Trazadone dose

IR 150-400mg/d in div doses

ER 150-375mg qHS

Sleep: 50-100mg qhs

Nefazadone dosing

200-600mg/d div BID

Aripiprazole dose

2-5mg/d qam; max 15mg/d

Symbyax dose

6/25mg qHS; can increase cautiously

Quetiapine dose

50mg qHs; can increase to 150-300mg qHS

Brexpiprazole dose

0.5-1mg/d, can titrate up weekly to 3mg/d

Cariprazine dose

1.5mg/d, can increase up to 3mg/d on Day 15

Esketamine (generic)

spravato (brand)

Esketamine dose

56 mg intransally twice weekly; can increase up to 84mg twice weekly IF tolerated

Esketamine counseling/notes

Must be adminstered under supervision; monitor for adverse effects for at least 2 horus after admin