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Cell membrane =
Regulates movement of substances (ions/compounds/elements)
Fluid mosaic model
Is the structure and organization of the plasma/cell membrane
Phospholipid bilayer (the fluid component)
Arranged in bilayer (hydrophophilic heads, hydrophobic tails)
Membrane proteins & carbohydrates (the mosaic component)
embedded within or associated with The lipid bilayer
Peripheral (Surface)
Integral (embedded)
Protein to phospholipid ratio
1 protein per 25 phospholipids
Cell surface markers
Specific proteins or glycoproteins displayed on the cell surface act as ID tags
Integral proteins
Deeply embedded tunnels that move materials
Peripheral proteins
Surface anchors that help with signals
Carbon hydrates
Surface “ID tags” (glycoproteins and glycolipids)
Peripheral membrane protein
Are at the plasma membrane’s surface either on its exterior or intention side
Anchored membrane protiensss
A lipid tail keeps the proteins tucked into the membrane
Glycolipid
Carbohydrate attached to a lipid
Glycoproteins
Carbohydrates attached to protein
Proteoglycan
Proteins with many long carbohydrate chains
Cholesterol
Attached between phopholipid and between the two phospholipid layers
Intergins
Embedded within the phospholipid layer ; may or may not penetrate through both layers
Which plasma membrane component can be either found on its surface or embedded in the membrane structure
Protein
What is the primary function of carbohydrates attached to the exterior of cell membranes
Identification of the cell
Lateral movement
Phospholipids slide side to side
Flip flop movement
Molecules shift between the inner and outer layer
Anchored
No movement
Non-anchored
Movement
Saturated (Viscous)
all single bonds between carbons
Lower permeability
Unsaturated (fluid)
Presence of carbon double bond
Cannot pack tightly
Higher permeability
In the fluid mosaic model, why is the membrane described as fluid
The phospholipids and proteins can move around laterally within the layer
By energy; passive
No energy needed. Molecule flow naturally
By energy; active
Needs energy to push molecules uphill
By direction; Uniport
Moves one molecule at a time
By direction ; symport
Move two different molecules in the same direction
Antiport ; by direction
Moves two different molecules in opposite directions
Transport process involves a single enzyme or transporter
Individual ; enzymatic activity
Transport process involves multiple enzymes or transporter proteins
Linked groups
Signal transduction
Cells receive and responds to signals
The receptor
A protein on the outside catches a specific signal
The relay
The protein changes shape and passes the message
The response
The call acts on the message like growin, moving, or making new stuff ?
Proteins hook onto the cytoskeleton to maintain its shape
Internal support
Proteins also grab the extracellular matrix
The cell membrane is selectively permeable. What type of molecules can diffuse directly across the lipid layer
Non polar
Cell junction
The specific door, bolt or vent connecting two buildings
Tight junction
Creates a firm seal between two adjacent animals cells
Desmonsomes
Provide intense mechanical strength
Gap junction
Direct channel between two adjacent animals cells that allowing and nutrient to pass between cells