Pharm CNS, Anti-fungals

zolpidem

what is the CNS depressant that is most often given in the hospital to help a pt go to sleep

pam, lam

what are the endings for benzodiazepines?

Enhances GABA

what is the MOA of Benzodiazepines

ETOH, CNS drugs, Opioids

what are the main interactions that can occur with benzodiazepines

Allergy, Pregnancy, Narrow-angle glaucoma

what are the three main contraindications for Benzodiazepines

Diazepam

what is the drug of choice for status epilepticus

Diazepam

what is the prototype benzodiazepine

Flumazenil

what is the antidote for benzodiazepines

severe respiratory depression

what is the big problem that can occur for a patient that OD's on diazepam

barbital

what is the ending for barbiturates

Reduce nerve pulse transmission, enhances GABA

what are the two MOA of Barbiturates

Seizures, Anesthesia

what are the two main Tx's for barbiturates

Respiratory arrest

what is the most critical SE of barbiturates

REM sleep loss, Resp Depression, Pregnancy

what are the three main nursing considerations for barbiturates

Baclofen

what is the centrally acting muscle relaxant that decreases nerve transmission to the spinal cord

Cyclobenzaprine

what is the centrally acting muscle relaxant that is used most often for people who hurt their backs

Tizanidine

what is the centrally acting muscle relaxant that stimulates Alpha 2 which inhibits nerve transmission

Dantrolene

what is the direct-acting muscle relaxant that works directly on the muscles to relax them

Convulsions

what are involuntary spasms of any or all skeletal muscle throughout the body

Control/prevent seizures, minimize SE/toxicity

what are the two goals for Antiepileptic drugs

Phenytoin

what is the prototype AED

carbamazepine

what is the 2nd most commonly prescribed anti-epileptic

NS

what is the only mixture that phenytoin can be given with?

10-20mcg/mL

what is the therapeutic level of phenytoin

4-12mcg/mL

what is the therapeutic level of Carbamazepine

50-100mcg/mL

what is the therapeutic level for Valproic acid

Lamotrigine/Gabapentin

what are the two newed AEDs that can be given during pregnancy

15-40mcg/mL

what is the therapeutic level of phenobarbital

sulfa

what do sulfonamides start with

Sulfonamides, Penicillins

what are the two anti-fungals that are known for causing allergies

Sulfonamides

which drug inhibits bacteria that produce folic acid

cillin

what is the ending for Penicillins

ceph/cef

what do cephalosporins start with?

penem

what is the ending of Carbapenems

am

What is the ending for monobactam

thromycin

what is the ending for macrolides

prolonged QT interval

what is the main SE of macrolides

micin/mycin

what is the ending for aminoglycosides

cycline

what is the ending for Tetracyclines

Vancomycin

what is the antibiotic that is very toxic

floxacin

what is the the ending for quinolones

Metronidazole

what is the drug that is most often given to treat c. diff

Rifampin, Isoniazid, Pyrazinamide, Ethambutol, Streptomycin

what are the first line Anti-tuberculars?

Penicillin, Sulfonamide, Cephalosporin, tetracyclines, Rifampin

what are the three drugs that decrease BCP's

macrolides, quinolones

what are the two drugs that cause a prolonged QT interval

Quinolones, Tetracyclines, Sulfonamides

what are the three drugs that cause photosensitivity

liver

what is the main organ that is heavily affected by antituberculars

inhibit viral replication

what is the MOA of antivirals

Acyclovir

what is the prototype antiviral

Oseltamivir, Zanamivir

what two antivirals are most often given to treat the flu

VIR

what is the ending for antivirals?

zidovudine, amprenavir, enfurvirtide, maraviroc, raltegravir

what are the five different anti-retrovirals?

Zidovudine

what is the prototype anti-retrovirals

azole

what is the ending for anti-fungals

Amphotericin B

what is the anti-fungal that is only given for a severe systemic infection with a fungus

Nystatin

what is the anti-fungal that is given for skin fungus infections

Streptomycin, Vancomycin

what are the two classes of drugs that should have their trough levels checked?