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INCLUDES ALL SECTIONS: 4.1 - The Chemist’s View of Carbohydrates 4.2 - Digestion and Absorption of Carbohydrates 4.3 - Glucose in the Body 4.4 - Health Effects and Recommended Intakes of Sugars 4.5 - Health Effects and Recommended Intakes of Starch and Fibers
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monosaccharides
Single sugar molecules
disaccharides
pairs of monosaccharides chemically bonded together
polysaccharides
large macromolecules formed from monosaccharides (chains of monosaccharides)
1 bond
how many atoms of hydrogen can form a chemical bond?
2 bonds
how many atoms of oxygen can form a chemical bond?
3 bonds
how many atoms of nitrogen can form a chemical bond?
4 bonds
how many atoms of carbon can form a chemical bond?
simple sugars, simple carbohydrates
what are some alternative names for monosaccharides?
glucose, fructose, galactose
what are the three most nutritionally important monosaccharides?
the structure of the monosaccharide
what accounts for differing tastes?
fructose?
which monosaccharide is the sweetest?
galactose?
which monosaccharide is the most bland?
glucose
commonly known as blood sugar; serves as an essential energy source for all bodily functions
fructose
a natural form of sugar responsible for the sweetness of fruits
galactose
monosaccharide that occurs naturally in foods as a single sugar only in very small amounts
maltose, sucrose, lactose
what are the three most nutritionally important disaccharides?
condensation
chemical reaction that links two monosaccharides together, via dehydration synthesis
hydrolysis
chemical reaction that breaks a disaccharide in two; also occurs in digestion
maltose
a disaccharide composed of two glucose units; product of starch digestion and alcohol fermentation; notably high in barley
sucrose
a disaccharide composed of glucose and fructose; accounts for natural sweetness of fruits, vegetables, and grains
lactose
a disaccharide composed of glucose and galactose; also known as "milk sugar"; principal carbohydrate of milk
glycogen, starches, and fibers
what are the three most nutritionally important polysaccharides?
glycogen
an extensively branched glucose storage polysaccharide found in the liver and muscle of animals; the animal equivalent of starch.
starch
long, branched or unbranched chained glucose storage polysaccharide found in plants; the plant equivalent of glycogen
amylose
a linear or straight-line polymer of glucose; form of starch
amylopectin
a branched chain of glucose; form of starch
fibers
found in plant foods, the nonstarch polysaccharides that are not digested by human digestive enzymes, although some are digested by GI tract bacteria
solubility, viscosity, fermentability
dietary fibers are classified by?
soluble fibers
nonstarch polysaccharides that dissolve in water to form a gel; benefit heart disease, diabetes, cancers, and weight management
insoluble fibers
nonstarch polysaccharides that do not dissolve in water; benefit GI health
viscous fibers
fibers that have gel-forming properties in the GI tract
fermentable fibers
fibers that can be digested by bacteria in the GI tract
soluble fibers, insoluble fibers
order fibers by most viscous and fermentable
dietary fibers
fibers naturally occurring and eaten in foods
functional fibers
manufactured or extracted fibers that are added to foods or supplements for beneficial health effects
total fiber
the sum of dietary and functional fibers
polysaccharides
in digestion, which class of carbohydrate requires extensive breakdown?
disaccharides
in digestion, which class of carbohydrates only need to be broken once?
monosaccharides
in digestion, which class of carbohydrates do not need to be broken down at all?
to break them into small molecules—mostly glucose—that the body can absorb and use (breakdown carbohydrates in food into monosaccharides)
what is the ultimate goal of digestion and absorption of sugars and starches?
long chains to shorter chains, short chains to disaccharides, and disaccharides to monosaccharides
describe the order of which enzymes hydrolyze starch
starch to shorter polysaccharides, polysaccharides to shorter chains and maltoses
describe the order of which salivary amylase hydrolyzes starch
the stomach's acid and protein-digesting enzymes
what inactivates salivary amylase?
in the stomach
where does carbohydrate digestion cease?
the small intestine
where does most digestion of carbohydrates take place?
pancreatice amylase
what breaks down the polysaccharides to shorter glucose chains and maltose?
maltase
a digestive enzyme that breaks disaccharide maltose into glucose
sucrase
a digestive enzyme that breaks disaccharide sucrose into glucose and fructose
lactase
a digestive enzyme that breaks disaccharide lactose into glucose and galactose
fibers
what isn't digested in the small intestine, but slows absorption to prevent surges in blood glucose levels?
nondigestible carbohydrates
what carbs remain in the large intestine (colon) as digestive activities slow to a halt?
the lingering fiber
attracts water and creates bulk, which softens the stools for passage without straining in the colon
bacteria in the GI tract
ferments some fibers, which generates water, gas, and short-chain fatty acids
resistant starches
starches that escape digestion and absorption
FODMAPs
a group of carbohydrates that is not digestible by the GI tract: fermentable oligosaccharides, disaccharides, monosaccharides, and polyols; shown to have negative gut effects such as stomach pain, bloating, indigestion, diarrhea, and/or constipation.
enterocytes
lining cells of the small intestine where most nutrient absorption takes place
active transport
energy-requiring transport of materials against the concentration gradient/difference
facilitated transport
passive transport of materials down the concentration gradient/difference
glucose and galactose
monosaccharides absorbed via active transport (may also via facilitated transport after high-carb meals) in the small intestine
fructose
monosaccharide absorbed by facilitated transport in the small intestine
blood
what carries monosaccharides to the liver?
the liver
where are fructose and glucose mostly metabolized (converted into glucose by hepatocytes), and glucose is then sent out to the body's cells for energy?
lactose intolerance
an inability to completely digest lactose, due to an insufficient amount of lactase
about 35%
what percentage of people can retain lactase to digest and absorb lactose efficiently?
6g of lactose (1/2 cup of milk) daily
how much lactose can lactose intolerant individuals consume daily?
to provide energy
primary role of glucose in the body
sugars attached to a protein change the protein's shape and function
sugars bind to lipids in a cell's membrane to alter the ways cells recognize one another
what are some additional roles that glucose and other sugars perform?
glycogen
the stored form of glucose that's made up of many connected glucose molecules
as glycogen in the liver, skeletal muscles, and the brain
how and where can excess glucose in the blood be stored?
25%
how much excess glucose is stored in the liver?
storage: excess glucose (single molecules) are condensed into long-branching chains of glycogen release: when blood glucose falls, glycogen is broken down into single molecules of glucose into the bloodstream
how does the liver store and release glycogen?
75%
how much excess glucose is stored in skeletal muscles?
primarily used during high-intensity exercise, meaning its used within the muscles themselves
how is glycogen used in skeletal muscles?
the brain only maintains a small amount, and its thought to provide an emergency energy reserve during times of severe glucose deprivation
how much glycogen is stored in the brain, and what's it's purpose?
the body converts it to fat, which serves as long-term energy reserves
what happens when a lot of excess glucose is present?
via cellular respiration, glucose is broken into smaller compounds that yield energy, which byproducts carbon dioxide and water
how does glucose fuel the work of most of the body's cells?
50-100 g/day
what's an adequate dietary intake of carbohydrates?
body proteins are broken down to make glucose, via gluconeogenesis, to fuel the brain and other nerve cells
what occurs when an individual does not replenish glucose by eating carbs?
the liver and skeletal muscles
where are body proteins deprived primarily from during gluconeogenesis?
protein-sparing action
what is the role of adequate dietary carbohydrate to prevent the use of protein for energy?
ketone bodies
compounds produced during the incomplete breakdown of fat when glucose is not available in the cells
ketosis/ketoacidosis
what occurs when the production of ketone bodies exceeds their use and accumulate in the blood?
it acidifies the blood
what effect does ketosis have in the blood?
cells need a constant supply of glucose from good and glycogen breakdown
how does the body sustain glucose homeostasis?
pancreas
what organ produces glucose-regulating hormones?
insulin, glucagon, and epinephrine
what are some glucose-regulating hormones?
insulin
a hormone secreted by the pancreatic beta cells that lower blood sugar levels by facilitating the uptake of glucose into tissues
insulin
what moves glucose from the blood into cells, stimulates glycogen formation in the liver, and stimulates conversion of glucose to fat?
glucagon
a hormone secreted by the pancreatic alpha cells that raise blood sugar level/glucose concentration; also stimulates glycogen breakdown
epinephrine
a hormone produced by adrenal glands (above the kidneys) that stimulates the liver to release glucose in times of stress
adrenaline
an alternative name for epinephrine hormone, which stimulates energy in emergencies
diabetes
a condition in which the body fails to regulate persistent high blood glucose levels
Type 1
type of diabetes where genetic & viral autoimmune destruction of endocrine cells occurs, and is insulin dependent?
Type 2
common type of diabetes where cells fail to respond to insulin, as a strong correlation with overweight/obesity
weight loss, exercise, and diet before meds
how is type 2 diabetes managed?
hypoglycemia
abnormally low blood glucose (level of sugar in the blood)
diabetes, exercise, fasting, illness, pancreatic tumors, alcohol abuse
what are some causes of hypoglycemia?
bodily weakness, fast heartbeat, sweating, anxiety, hunger, bodily shaking
what are some symptoms of hypoglycemia?
milligrams per deciliter mg/dL
a unit of measure that describes the concentration of substance (glucose) in a specific amount of fluid (blood)
<70 mg/dL
FBG levels diagnostic of hypoglycemia