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DNA Replication
DNA replicates during the S phase of the cell cycle
the alternative models of DNA replication are conservative, semi conservative, and dispersive
the correct one for DNA is semi conservative

Conservative model
the parental strands direct synthesis of an entirely new double stranded molecule
the parental strands are fully “conserved”

Semi conservative model
the two parental strands each make a copy of itself
after one round of replication, the 2 daughter molecules each have 1 parental and 1 new strand

Dispersive model
the material in the two parental strands is dispersed randomly between the 2 daughter molecules
after one round of replication, the daughter molecules contain a random mix of parental and new DNA

Origins of replication
DNA replication begins at sites called origins of replication
prokaryotes have one origin of replication, eukaryotes have many
various proteins attach to the origin of replication and open the DNA to form a replication fork
